Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.58 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942537 | 0.86 | TGFBR1 (0.59) | STSTGFBR1GPR119CACNA1B | |
| SCHEMBL15103494 | 0.83 | GPR119 (0.56) | STSGPR119 | |
| SCHEMBL17942389 | 0.83 | TGFBR1 (0.53) | STSTGFBR1GPR119 | |
| SCHEMBL7787142 | 0.82 | STS (0.59) | STSTGFBR1GPR119CACNA1BDPP4 | |
| SCHEMBL22585196 | 0.82 | GPR119 (0.53) | GPR119 | |
| SCHEMBL2920158 | 0.78 | STS (0.62) | STSTGFBR1GPR119RORCSCN9A | |
| SCHEMBL7787129 | 0.78 | STS (0.48) | STSTGFBR1GPR119DPP4SCN9A | |
| SCHEMBL4153384 | 0.78 | GPR119 (0.49) | STSTGFBR1GPR119 | |
| SCHEMBL10265584 | 0.78 | GPR119 (0.57) | STSGPR119 | |
| SCHEMBL22585205 | 0.77 | GPR119 (0.57) | GPR119SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234603-A1 | Process for Making Substituted Aryl Sulfone Intermediates | LINGHU XIN | 2010-09-16 | — | — | US | disclosed |
| US-20100234604-A1 | Process for Making Substituted Aryl Sulfone Intermediates | LINGHU XIN | 2010-09-16 | — | — | US | disclosed |
| US-20100234604-A1 | Process for Making Substituted Aryl Sulfone Intermediates | LINGHU XIN | 2010-09-16 | — | — | US | disclosed |
| US-20100234603-A1 | Process for Making Substituted Aryl Sulfone Intermediates | LINGHU XIN | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234604-A1 | Process for Making Substituted Aryl Sulfone Intermediates | SULT1A1, SULT1E1, STS | STS 3/4885TGFBR1 4018/4885GPR119 4733/4885 |
| US-20100234603-A1 | Process for Making Substituted Aryl Sulfone Intermediates | SULT1A1, SULT1E1, STS | STS 3/4885TGFBR1 4018/4885GPR119 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.