Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786050 | 0.80 | MAPT (0.36) | — | |
| SCHEMBL29439088 | 0.79 | HTR2A (0.49) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL4311498 | 0.79 | HTR2A (0.49) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL4311675 | 0.79 | HTR2A (0.49) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL8422197 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HPGDCHRNB2CHRNA4HTR2A | |
| SCHEMBL1583058 | 0.79 | HTR2A (0.49) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL7784244 | 0.76 | HTR2A (0.51) | HPGDCHRNB2CHRNA4SLC6A4HTR2A | |
| SCHEMBL17865235 | 0.76 | BRD4 (0.38) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1437913 | 0.76 | NPC1 (0.43) | ALDH1A1NPC1RAB9A | |
| SCHEMBL8289625 | 0.75 | CHRNB2 (0.41) | ALDH1A1HPGDCHRNB2CHRNA4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |