SCHEMBL7787351

SCHEMBL7787351

N#Cc1ccc(Cc2ccc(C#N)c(Cl)c2)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.55
CYP3A4 P08684 1/20 0.48
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
ADRA1D P25100 1/20 0.43
AR P10275 7/20 0.42
CYP11B2 P19099 2/20 0.42
SNCA P37840 1/20 0.42
IDO1 P14902 1/20 0.41
KCNJ1 P48048 1/20 0.41
KCNH2 Q12809 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.39
SLC22A12 Q96S37 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18130645 0.84 LOXL2 (0.50) TRPV4MAOAMAOBNOS3NOS1
SCHEMBL2569992 0.83 TRPV4 (0.52) TRPV4MAOAMAOBNOS3NOS1
SCHEMBL5047623 0.83 TRPV4 (0.52) TRPV4MAOAMAOBNOS3NOS1
SCHEMBL12189123 0.83 TRPV4 (0.52) TRPV4MAOAMAOBNOS3NOS1
SCHEMBL5099511 0.83 TRPV4 (0.52) TRPV4MAOAMAOBNOS3NOS1
SCHEMBL24108441 0.83 TRPV4 (0.52) TRPV4MAOAMAOBNOS3NOS1
Hydrochloric Acid SCHEMBL18130460 0.83 LOXL2 (0.48) TRPV4CYP3A4MAOAMAOBNOS3
SCHEMBL21384114 0.82 NOS3 (0.47) TRPV4CYP3A4NOS3NOS1ADRA1D
SCHEMBL29442855 0.82 NOS3 (0.47) TRPV4CYP3A4NOS3NOS1ADRA1D
SCHEMBL6805165 0.82 AR (0.58) TRPV4ADRA1DARMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112955302-B Method for manufacturing a laminate with partial curing 斯特拉塔西斯公司 2023-05-02 CN disclosed
CN-112930257-B Three-dimensional inkjet printing of thermally stable objects 斯特拉塔西斯公司 2023-03-24 CN disclosed
CN-112955302-A Method for build-up manufacturing with partial curing 斯特拉塔西斯公司 2021-06-11 CN disclosed
CN-112930257-A Three-dimensional inkjet printing of thermally stable objects 斯特拉塔西斯公司 2021-06-08 CN disclosed
US-20090197202-A1 PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-08-06 US disclosed
JP-2001316584-A NORMAL TEMPERATURE SETTING TWO-PART POLYURETHANE RESIN COMPOSITION AND PAVING MATERIAL USING THE SAME SUMITOMO RUBBER IND LTD 2001-11-16 JP disclosed
EP-0594644-B1 ANISOTROPIC CONDUCTIVE ADHESIVE FILM MINNESOTA MINING & MFG (US) 1997-03-12 EP disclosed
EP-0594644-A1 ANISOTROPIC CONDUCTIVE ADHESIVE FILM. MINNESOTA MINING & MFG (US) 1994-05-04 EP disclosed
WO-1993001248-A1 ANISOTROPIC CONDUCTIVE ADHESIVE FILM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-01-21 WO disclosed