Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7787514 | 0.99 | CA1 (0.36) | CA1CA2ACHECSF1RMEN1 | |
| SCHEMBL7787471 | 0.90 | BCL9 (0.36) | CA1CA2ACHECSF1RMEN1 | |
| SCHEMBL7787770 | 0.90 | KMT2A (0.40) | MEN1POLBKMT2AMAPKAPK2MAPK14 | |
| SCHEMBL7785696 | 0.90 | KMT2A (0.40) | MEN1POLBKMT2AMAPKAPK2MAPK14 | |
| SCHEMBL7785675 | 0.90 | KMT2A (0.40) | MEN1POLBKMT2AMAPKAPK2MAPK14 | |
| Hydrochloric Acid SCHEMBL7787718 | 0.89 | KMT2A (0.40) | MEN1POLBKMT2AMAPKAPK2MAPK14 | |
| SCHEMBL7780728 | 0.88 | MAPKAPK2 (0.37) | MEN1POLBKMT2AIDO1MAPKAPK2 | |
| SCHEMBL7789355 | 0.85 | MAPKAPK2 (0.46) | IDO1MAPKAPK2MAPK14AURKB | |
| SCHEMBL7780560 | 0.81 | ALDH1A1 (0.44) | MEN1POLBKMT2AMAPKAPK2EGFR | |
| SCHEMBL7787655 | 0.81 | ALDH1A1 (0.44) | MEN1POLBKMT2AMAPKAPK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |