SCHEMBL7787700

SCHEMBL7787700

O=C(c1ccc(Cl)cc1)C1C=CC=CC1(Cl)S(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
MAPT P10636 2/20 0.35
TP53 P04637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CES2 O00748 3/20 0.34
CES1 P23141 3/20 0.34
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
MGLL Q99685 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
FLT1 P17948 1/20 0.33
FLT4 P35916 1/20 0.33
KDR P35968 1/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
SRD5A2 P31213 1/20 0.31
GSK3B P49841 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782806 0.68 NPC1 (0.37) MAPTL3MBTL1CES2CES1ALOX15
SCHEMBL7788590 0.68 HTT (0.31) MAPTL3MBTL1CES2CES1ALOX15
SCHEMBL8345761 0.68
SCHEMBL7782761 0.67 L3MBTL1 (0.36) MAPTL3MBTL1ALOX15TSHR
SCHEMBL7787651 0.67 NPC1 (0.39) MAPTTP53L3MBTL1CES2CES1
SCHEMBL2717876 0.66
SCHEMBL7768283 0.64
SCHEMBL29067489 0.64 NPC1 (0.41) MAPTL3MBTL1CES2CES1ALOX15
SCHEMBL1874394 0.63 MAPT (0.38) LMNAMAPTL3MBTL1CES2MGLL
SCHEMBL11371672 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3395323-B1 METHOD FOR TREATING HAIR KAO CORP (JP) 2021-09-29 EP disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 US disclosed
EP-3395323-A1 HAIR TREATMENT METHOD Kao Corporation (JP) 2018-10-31 EP disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 EP disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 LMNA 2120/4885MAPT 1450/4885TP53 1727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.