SCHEMBL7787651

SCHEMBL7787651

CC1(S(=O)(=O)O)C=CC=CC1C(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 2/20 0.33
ALOX15 P16050 1/20 0.33
HBB P68871 1/20 0.33
EPHX1 P07099 1/20 0.32
KMT2A Q03164 2/20 0.31
HSD11B1 P28845 1/20 0.30
GAA P10253 2/20 0.30
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
MAPK1 P28482 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782806 0.81 NPC1 (0.37) NPC1L3MBTL1HTTSMN1; SMN2MAPT
SCHEMBL7782761 0.79 L3MBTL1 (0.36) NPC1L3MBTL1HTTMAPTALOX15
SCHEMBL28014454 0.78 NPC1 (0.42) NPC1L3MBTL1HTTSMN1; SMN2MAPT
SCHEMBL29067489 0.77 NPC1 (0.41) NPC1L3MBTL1HTTSMN1; SMN2MAPT
SCHEMBL31050429 0.75 NPC1 (0.40) NPC1L3MBTL1HTTSMN1; SMN2MAPT
SCHEMBL1828048 0.74 L3MBTL1 (0.41) NPC1L3MBTL1HTTSMN1; SMN2MAPT
SCHEMBL7851780 0.74 L3MBTL1 (0.41) NPC1L3MBTL1HTTSMN1; SMN2MAPT
SCHEMBL20506049 0.74 NPC1 (0.33) NPC1L3MBTL1
SCHEMBL31157635 0.73 NPC1 (0.39) NPC1L3MBTL1HTTSMN1; SMN2MAPT
SCHEMBL4621722 0.73 NPC1 (0.40) NPC1L3MBTL1HTTSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220226216-A1 HAIR TREATMENT METHOD KAO CORPORATION (JP) 2022-07-21 US disclosed
EP-3998060-A1 HAIR COSMETIC Kao Corporation (JP) 2022-05-18 EP disclosed
US-11234916-B2 Hair cosmetic KAO CORPORATION (JP) 2022-02-01 US disclosed
EP-3395323-B1 METHOD FOR TREATING HAIR KAO CORP (JP) 2021-09-29 EP disclosed
US-20210069081-A1 HAIR COSMETIC KAO CORPORATION (JP) 2021-03-11 US disclosed
EP-3741352-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 2020-11-25 EP disclosed
WO-2019142815-A1 HAIR COSMETIC COMPOSITION 花王株式会社 2019-07-25 WO disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 US disclosed
EP-3395323-A1 HAIR TREATMENT METHOD Kao Corporation (JP) 2018-10-31 EP disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 EP disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210069081-A1 HAIR COSMETIC TYR, CUTA, H1-0 NPC1 3435/4885L3MBTL1 3837/4885HTT 160/4885
US-20220226216-A1 HAIR TREATMENT METHOD POLR1C, ALDH7A1, CA7 NPC1 2627/4885L3MBTL1 2976/4885HTT 1961/4885
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 NPC1 4569/4885L3MBTL1 4594/4885HTT 1060/4885
US-11234916-B2 Hair cosmetic TYR, CUTA, H1-0 NPC1 3435/4885L3MBTL1 3837/4885HTT 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.