SCHEMBL778772

SCHEMBL778772

Cc1ccc(S(=O)(=O)O)cc1CC(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.38
ALDH1A1 P00352 9/20 0.37
TSHR P16473 2/20 0.37
NT5E P21589 1/20 0.37
HSD17B10 Q99714 4/20 0.37
TDP1 Q9NUW8 2/20 0.37
SNCA P37840 1/20 0.36
LMNA P02545 3/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
PHLPP2 Q6ZVD8 1/20 0.33
CYP2C19 P33261 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775756 0.87 ALDH1A1 (0.35) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL658698 0.85 ALDH1A1 (0.38) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL8916748 0.84 ALDH1A1 (0.35) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL10377767 0.84 ALDH1A1 (0.33) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL776684 0.84 SNCA (0.35) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL776515 0.81 SNCA (0.39) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL10596213 0.80 ALDH1A1 (0.41) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL1607817 0.80 ALDH1A1 (0.41) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL10318598 0.80 LMNA (0.35) ALDH1A1TSHRNT5EHSD17B10TDP1
SCHEMBL9419143 0.79 ALOX15 (0.35) PTGS2ALDH1A1HSD17B10SNCALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954709-A Preparation method of sulfoxide compound, aniline compound and preparation method of aniline compound 帕潘纳(北京)科技有限公司 2025-05-09 CN claimed
CN-110556509-A Method for performing surface protection and passivation treatment on metallic lithium cathode by using fluorine-containing organic matter, product and application NANJING UNIVERSITY OF TECHNOLOGY 2019-12-10 CN claimed
JP-60092260-A None JP disclosed
CN-119954709-A Preparation method of sulfoxide compound, aniline compound and preparation method of aniline compound 帕潘纳(北京)科技有限公司 2025-05-09 CN disclosed
CN-118235084-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-06-21 CN disclosed
CN-118103209-A Composition for forming release layer, laminate, and method for producing laminate 日产化学株式会社 2024-05-28 CN disclosed
CN-118020019-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-05-10 CN disclosed
WO-2024041555-A1 METHODS OF MANUFACTURING KINASE INHIBITORS INSILICO MEDICINE IP LIMITED (CN) 2024-02-29 WO disclosed
CN-117015582-A Composition for forming release layer and release layer 日产化学株式会社 2023-11-07 CN disclosed
CN-116789871-A Composition for forming cured film, alignment material, and retardation material 日产化学株式会社 2023-09-22 CN disclosed
CN-112384834-B Cured film, alignment material, and retardation material 日产化学株式会社 2023-08-11 CN disclosed
US-4754067-A REACTING A SYMETRICAL DIAMINOGUANIDINE WITH HYDROXYLAMINE HYDROCHLORIDE AMERICAN CYANAMID COMPANY (US) 1988-06-28 US disclosed
EP-0169571-B1 PHENYLNONATETRAENIC-ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1988-03-09 EP disclosed
US-4649148-A Insecticidal uses of diaminoguanidine hydrazone compounds AMERICAN CYANAMID COMPANY (US) 1987-03-10 US disclosed
US-4648996-A ANTIRHEUMATIC AGENTS, IMMUNOSUPRESSANTS HOFFMANN-LA ROCHE INC. (US) 1987-03-10 US disclosed
US-4575560-A ANTIFEEDING AGENTS AMERICAN CYANAMID COMPANY (US) 1986-03-11 US disclosed
EP-0097270-B1 ORGANOPHOSPHATE DERIVATIVES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-08-28 EP disclosed
EP-0143302-A2 Benzoylurea derivatives and intermediates NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-06-05 EP disclosed
JP-S6092260-A NOVEL BENZOYLUREA DERIVATIVE, ITS INTERMEDIATE, THEIR PREPARATION AND INSECTICIDE NIPPON TOKUSHU NOYAKU SEIZO KK 1985-05-23 JP disclosed
EP-0097270-A1 Organophosphate derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1984-01-04 EP disclosed