Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18571270 | 0.81 | ALDH1A1 (0.41) | TDP1ALDH1A1CA1CA2MMP1 | |
| SCHEMBL4772456 | 0.79 | ALDH1A1 (0.46) | TDP1ALDH1A1CA1CA2HDAC8 | |
| SCHEMBL8433473 | 0.77 | ALDH1A1 (0.44) | TDP1ALDH1A1CA1CA2HDAC8 | |
| SCHEMBL8261072 | 0.76 | HPGD (0.48) | ALKBH5CA1CA2MMP1MMP2 | |
| SCHEMBL9046172 | 0.76 | GAA (0.48) | ALDH1A1ALKBH5CA1CA2MMP1 | |
| SCHEMBL24140260 | 0.75 | HPGD (0.47) | ALDH1A1ALKBH5CA1CA2MMP1 | |
| SCHEMBL14536541 | 0.75 | ALDH1A1 (0.46) | TDP1ALDH1A1CA1CA2HDAC8 | |
| SCHEMBL16738666 | 0.75 | ESR1 (0.46) | ALDH1A1ALKBH5CA1CA2MMP1 | |
| SCHEMBL955244 | 0.75 | PSIP1 (0.48) | ALKBH5CA1CA2MMP1MMP2 | |
| SCHEMBL4573162 | 0.75 | ALKBH5 (0.42) | ALDH1A1ALKBH5CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017034982-A1 | DERIVATIVES OF HALO QUINABACTIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-02 | — | — | WO | disclosed |
| EP-0731388-B1 | An energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material | AT & T CORP (US) | 2001-11-14 | — | — | EP | disclosed |
| US-5656412-A | Energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material | LUCENT TECHNOLOGIES INC. (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0731388-A2 | An energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material | AT&T Corp. (US) | 1996-09-11 | — | — | EP | disclosed |