Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780673 | 0.92 | MAPKAPK2 (0.46) | MEN1KMT2APOLBMAPKAPK2THRA | |
| SCHEMBL7789136 | 0.92 | MAPKAPK2 (0.46) | MEN1KMT2APOLBMAPKAPK2THRA | |
| Hydrochloric Acid SCHEMBL7787875 | 0.91 | MEN1 (0.45) | MEN1KMT2APOLBMAPKAPK2THRA | |
| Hydrochloric Acid SCHEMBL7780320 | 0.90 | POLB (0.48) | MEN1KMT2APOLBMAPKAPK2THRA | |
| SCHEMBL7785296 | 0.89 | ALDH1A1 (0.46) | MEN1KMT2APOLBMAPKAPK2THRA | |
| SCHEMBL7789345 | 0.89 | ALDH1A1 (0.46) | MEN1KMT2APOLBMAPKAPK2THRA | |
| SCHEMBL7789329 | 0.88 | MEN1 (0.40) | MEN1KMT2APOLBMAPKAPK2THRA | |
| SCHEMBL7789161 | 0.88 | MEN1 (0.40) | MEN1KMT2APOLBMAPKAPK2THRA | |
| Hydrochloric Acid SCHEMBL7785704 | 0.88 | ALDH1A1 (0.45) | MEN1KMT2APOLBMAPKAPK2THRA | |
| Hydrochloric Acid SCHEMBL7795378 | 0.88 | MEN1 (0.40) | MEN1KMT2APOLBMAPKAPK2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |