Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789161 | 1.00 | MEN1 (0.40) | MEN1KMT2AGAAKDM4EGLA | |
| SCHEMBL7789338 | 0.92 | RCE1 (0.45) | ALDH1A1RCE1MAPKAPK2CDC25BLMNA | |
| Hydrochloric Acid SCHEMBL7780764 | 0.91 | RCE1 (0.47) | MEN1KMT2AALDH1A1POLBRCE1 | |
| SCHEMBL7780400 | 0.89 | RCE1 (0.40) | ALDH1A1RCE1MAPKAPK2 | |
| SCHEMBL7787509 | 0.89 | RCE1 (0.40) | ALDH1A1RCE1MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL7785684 | 0.89 | RCE1 (0.42) | ALDH1A1RCE1 | |
| SCHEMBL7780580 | 0.89 | RCE1 (0.40) | MEN1KMT2AALDH1A1MAPTRCE1 | |
| Hydrochloric Acid SCHEMBL7785319 | 0.88 | RCE1 (0.41) | MEN1KMT2AALDH1A1MAPTRCE1 | |
| Hydrochloric Acid SCHEMBL7787883 | 0.88 | RCE1 (0.41) | ALDH1A1RCE1MAPKAPK2 | |
| SCHEMBL7787895 | 0.88 | MEN1 (0.41) | MEN1KMT2AGAAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |