Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.45 |
| ▸ | ITGAV | P06756 | 8/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790187 | 0.96 | ITGB3 (0.43) | ITGB3ITGAVUSP2LMNAGAA | |
| SCHEMBL7788177 | 0.96 | ITGB3 (0.43) | ITGB3ITGAVUSP2LMNAGAA | |
| SCHEMBL7194908 | 0.85 | ITGB3 (0.51) | ITGB3ITGAVLMNASMN1; SMN2ITGA2B | |
| SCHEMBL7781101 | 0.84 | KMT2A (0.46) | ITGB3ITGAVLMNASMN1; SMN2POLB | |
| SCHEMBL14501731 | 0.83 | ITGB3 (0.44) | ITGB3ITGAVLMNAITGA2BCA1 | |
| SCHEMBL7788773 | 0.83 | ITGB3 (0.42) | ITGB3ITGAVLMNASMN1; SMN2CA1 | |
| SCHEMBL13715863 | 0.82 | PKM (0.46) | ITGB3ITGAVLMNAHPGDSMN1; SMN2 | |
| SCHEMBL7790184 | 0.82 | MEN1 (0.48) | ITGB3ITGAVLMNAHPGDSMN1; SMN2 | |
| SCHEMBL7789975 | 0.82 | ITGB3 (0.46) | ITGB3ITGAVLMNAHTTITGA2B | |
| SCHEMBL7191727 | 0.82 | ITGB3 (0.46) | ITGB3ITGAVSMN1; SMN2POLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |