Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194908 | 0.93 | ITGB3 (0.51) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL7790080 | 0.92 | MEN1 (0.52) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL7781212 | 0.91 | ITGB3 (0.48) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL7790184 | 0.91 | MEN1 (0.48) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL7785662 | 0.91 | MAPT (0.48) | ITGB3ITGA2BMEN1KMT2AMAPT | |
| SCHEMBL7781187 | 0.90 | GAA (0.47) | ITGB3ITGA2BMEN1KMT2AKCNA5 | |
| SCHEMBL7788290 | 0.89 | ITGB3 (0.43) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL7786217 | 0.88 | KMT2A (0.46) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL7788754 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL7785609 | 0.87 | LMNA (0.45) | ITGB3ITGA2BMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |