Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861486 | 0.94 | ALDH1A1 (0.65) | ALDH1A1RECQLATMPKMKDM4E | |
| SCHEMBL29166051 | 0.87 | FDPS (0.45) | ALDH1A1RECQLATMKDM4EMEN1 | |
| SCHEMBL28914937 | 0.82 | ALDH1A1 (0.89) | ALDH1A1RECQLATMPKMKDM4E | |
| SCHEMBL5779127 | 0.81 | PTPRB (0.49) | ALDH1A1RECQLKDM4EMAPK1MAPT | |
| SCHEMBL6870117 | 0.79 | ALDH1A1 (0.69) | ALDH1A1RECQLATMPKMKDM4E | |
| SCHEMBL5862781 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5140898 | 0.77 | CYP1A2 (0.48) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL10657871 | 0.77 | ALDH1A1 (0.67) | ALDH1A1RECQLATMPKMKDM4E | |
| SCHEMBL10657868 | 0.77 | ALDH1A1 (0.67) | ALDH1A1RECQLATMPKMKDM4E | |
| SCHEMBL10657875 | 0.77 | ALDH1A1 (0.67) | ALDH1A1RECQLATMPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |