Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789230 | 0.90 | KMT2A (0.36) | CRHBPCRHR2CASRALDH1A1KMT2A | |
| SCHEMBL7785066 | 0.89 | CRHBP (0.39) | CRHBPCRHR2CASRALDH1A1KMT2A | |
| SCHEMBL7785589 | 0.83 | MAPKAPK2 (0.45) | MAPKAPK2 | |
| SCHEMBL7785111 | 0.82 | CASR (0.45) | CRHBPCRHR2CASRALDH1A1KMT2A | |
| SCHEMBL7787494 | 0.80 | KMT2A (0.38) | CRHBPCRHR2CASRALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7787505 | 0.79 | MAPKAPK2 (0.34) | KMT2AMAPKAPK2CXCR2MEN1 | |
| SCHEMBL7787667 | 0.77 | MAPKAPK2 (0.46) | ALDH1A1KMT2AGAALMNAMAPKAPK2 | |
| SCHEMBL7780621 | 0.76 | MAPKAPK2 (0.38) | KMT2AMAPKAPK2CXCR2MEN1 | |
| SCHEMBL7787683 | 0.75 | MAPKAPK2 (0.45) | MAPKAPK2 | |
| SCHEMBL7787601 | 0.75 | MAPKAPK2 (0.45) | MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |