Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785112 | 0.87 | KMT2A (0.44) | CASRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL7789132 | 0.82 | CRHBP (0.39) | CASRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL7785680 | 0.80 | NPC1 (0.41) | ALDH1A1KMT2AMAPTLMNAMITF | |
| SCHEMBL7785173 | 0.80 | ALDH1A1 (0.45) | CASRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL7780321 | 0.78 | KMT2A (0.48) | CASRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL7785066 | 0.76 | CRHBP (0.39) | CASRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL7789230 | 0.75 | KMT2A (0.36) | CASRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL7785570 | 0.74 | KMT2A (0.40) | CASRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL7787498 | 0.74 | CA1 (0.34) | CASRKMT2AMAPTLMNAHTT | |
| SCHEMBL7785272 | 0.74 | KMT2A (0.41) | CASRALDH1A1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |