Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7780764 | 0.99 | RCE1 (0.47) | RCE1ALDH1A1MAPKAPK2L3MBTL1GRIN2D | |
| SCHEMBL7787509 | 0.93 | RCE1 (0.40) | RCE1ALDH1A1MAPKAPK2GRIN2DGRIN3B | |
| SCHEMBL7780400 | 0.93 | RCE1 (0.40) | RCE1ALDH1A1MAPKAPK2GRIN2DGRIN3B | |
| SCHEMBL7780580 | 0.93 | RCE1 (0.40) | RCE1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL7785684 | 0.93 | RCE1 (0.42) | RCE1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL7787883 | 0.92 | RCE1 (0.41) | RCE1ALDH1A1MAPKAPK2GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL7785319 | 0.92 | RCE1 (0.41) | RCE1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7789329 | 0.92 | MEN1 (0.40) | RCE1ALDH1A1MAPKAPK2CDC25BLMNA | |
| SCHEMBL7789161 | 0.92 | MEN1 (0.40) | RCE1ALDH1A1MAPKAPK2CDC25BLMNA | |
| SCHEMBL7789354 | 0.87 | MAPKAPK2 (0.45) | MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |