Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 3/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787509 | 1.00 | RCE1 (0.40) | RCE1TEAD4MAPKAPK2MAOAPTGER4 | |
| Hydrochloric Acid SCHEMBL7787883 | 0.99 | RCE1 (0.41) | RCE1TEAD4MAPKAPK2MAOAPTGER4 | |
| SCHEMBL7789338 | 0.93 | RCE1 (0.45) | RCE1MAPKAPK2ALDH1A1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL7780764 | 0.92 | RCE1 (0.47) | RCE1MAPKAPK2ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL7780580 | 0.91 | RCE1 (0.40) | RCE1PTGER4ALDH1A1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL7785684 | 0.91 | RCE1 (0.42) | RCE1TEAD4PTGER4ALDH1A1GRIN2D | |
| Hydrochloric Acid SCHEMBL7785319 | 0.90 | RCE1 (0.41) | RCE1PTGER4ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL7789161 | 0.89 | MEN1 (0.40) | RCE1MAPKAPK2ALDH1A1 | |
| SCHEMBL7789329 | 0.89 | MEN1 (0.40) | RCE1MAPKAPK2ALDH1A1 | |
| SCHEMBL7785292 | 0.87 | MAPKAPK2 (0.45) | TEAD4MAPKAPK2PTGER4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |