SCHEMBL8926730

SCHEMBL8926730

O=Cc1ccccc1-c1ccc(O)c(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.53
PTGER1 P34995 1/20 0.50
PTGER3 P43115 1/20 0.50
PTGER2 P43116 1/20 0.50
PTGS2 P35354 1/20 0.46
TRIM24 O15164 1/20 0.46
TRIM33 Q9UPN9 1/20 0.46
ERN1 O75460 5/20 0.44
APP P05067 1/20 0.44
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6260642 0.84 PTGER1 (0.62) PTGER1PTGER3PTGER2ERN1ADORA1
SCHEMBL21484877 0.84 APP (0.64) PTGS2TRIM24TRIM33ERN1APP
SCHEMBL3290493 0.80 PTGER3 (0.79) ESR2PTGER1PTGER3PTGER2MAPT
SCHEMBL12834084 0.80 ERN1 (0.57) TRIM24TRIM33ERN1MEN1NPC1
SCHEMBL1631167 0.80 PTGS2 (0.54) PTGER1PTGER3PTGER2PTGS2ERN1
SCHEMBL2560045 0.80 PTGER1 (0.54) PTGER1PTGER3PTGER2ERN1ALDH1A1
SCHEMBL7789344 0.78 ESR2 (0.64) ESR2PTGS2APPADORA2AADORA1
SCHEMBL17188186 0.78 ERN1 (0.46) TRIM24TRIM33ERN1APPMEN1
SCHEMBL11070801 0.77 PTGER1 (0.47) PTGER1PTGER3PTGER2PTGS2ERN1
SCHEMBL2477166 0.77 PTGER1 (0.47) PTGER1PTGER3PTGER2PTGS2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5681689-A COUPLING WITH OXIDIZED COLOR DEVELOPER EASTMAN KODAK COMPANY (US) 1997-10-28 US disclosed