Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.74 |
| ▸ | RXRB | P28702 | 4/20 | 0.74 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.55 |
| ▸ | BCL2 | P10415 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758879 | 0.85 | RXRA (1.00) | RXRARXRBMRGPRX4BCL2NR4A2 | |
| SCHEMBL18314425 | 0.85 | RXRA (1.00) | RXRARXRBMRGPRX4BCL2NR4A2 | |
| SCHEMBL9422520 | 0.84 | LTA4H (0.49) | RXRARXRBEGFRMRGPRX4NR4A2 | |
| SCHEMBL505652 | 0.83 | RXRA (0.72) | RXRARXRBBCL2RXRGPTGES | |
| SCHEMBL3148484 | 0.83 | KMT2A (0.66) | MRGPRX4NR4A2KMT2A | |
| SCHEMBL30278441 | 0.83 | RXRA (0.72) | RXRARXRBBCL2RXRGPTGES | |
| SCHEMBL6715351 | 0.82 | EGFR (0.52) | RXRARXRBEGFRMRGPRX4NR4A2 | |
| SCHEMBL6569708 | 0.82 | RXRA (0.78) | RXRARXRBMRGPRX4BCL2KMT2A | |
| SCHEMBL28853764 | 0.82 | RXRA (0.73) | RXRARXRBEGFRMRGPRX4BCL2 | |
| SCHEMBL5846151 | 0.81 | RARG (0.62) | RXRAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | disclosed |
| EP-0952974-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development (FR) | 1999-11-03 | — | — | EP | disclosed |
| WO-1999010308-A1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT (FR) | 1999-03-04 | — | — | WO | disclosed |