Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465218 | 0.89 | LMNA (0.57) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL6181962 | 0.82 | CTSS (0.50) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL6183204 | 0.81 | CTSS (0.49) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL6183160 | 0.81 | CTSS (0.49) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL8327496 | 0.80 | HTT (0.59) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL7456077 | 0.80 | CTSS (0.57) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL6183151 | 0.80 | SLC1A3 (0.52) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL6181806 | 0.80 | CTSS (0.57) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL7799710 | 0.79 | SLC1A3 (0.42) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL8324281 | 0.78 | LMNA (0.56) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |