Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468352 | 0.91 | LMNA (0.50) | SLC1A3SLC1A1LMNASMN1; SMN2FOLH1 | |
| SCHEMBL22982284 | 0.80 | MEN1 (0.47) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL5172763 | 0.80 | MEN1 (0.47) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL7044864 | 0.79 | SLC1A3 (0.41) | SLC1A3SLC1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6465943 | 0.79 | ANPEP (0.44) | SLC1A3SLC1A1LMNASMN1; SMN2FOLH1 | |
| SCHEMBL7790161 | 0.79 | LMNA (0.46) | SLC1A3SLC1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL7046317 | 0.78 | SLC1A3 (0.39) | SLC1A3SLC1A1LMNASMN1; SMN2FOLH1 | |
| SCHEMBL6181962 | 0.78 | CTSS (0.50) | SLC1A3SLC1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6062401 | 0.77 | L3MBTL1 (0.40) | SLC1A3SLC1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6063445 | 0.77 | PTGER4 (0.47) | SLC1A3SLC1A1LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |