Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447607 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEACHELMNATAAR1 | |
| SCHEMBL7203604 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEACHELMNATAAR1 | |
| SCHEMBL4350566 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEACHELMNATAAR1 | |
| SCHEMBL17541938 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEACHELMNATAAR1 | |
| SCHEMBL7203599 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEACHELMNATAAR1 | |
| SCHEMBL17541937 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEACHELMNATAAR1 | |
| SCHEMBL8080146 | 0.82 | LMNA (0.44) | ALDH1A1BCHEACHELMNATAAR1 | |
| SCHEMBL5213078 | 0.80 | CHRNB2 (0.42) | ALDH1A1BCHELMNATSHRMAPK1 | |
| SCHEMBL6784103 | 0.80 | CHRNB2 (0.42) | ALDH1A1BCHELMNATSHRMAPK1 | |
| SCHEMBL172658 | 0.80 | CHRNB2 (0.42) | ALDH1A1BCHELMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1151133-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | McGILL UNIVERSITY (CA) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047759-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC. (CA) | 2000-08-17 | — | — | WO | disclosed |