SCHEMBL7790218

SCHEMBL7790218

CCC(C)c1cc(-c2cc(C(C)CC)cc(C(C)CC)c2)cc(C(C)CC)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
GAA P10253 2/20 0.42
USP2 O75604 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
TSHR P16473 3/20 0.34
CYP2C9 P11712 1/20 0.34
RORC P51449 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
ALOX12 P18054 1/20 0.31
SCN10A Q9Y5Y9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11686432 0.91 ALDH1A1 (0.46) ALDH1A1GAAUSP2PKMHPGD
SCHEMBL9178609 0.79 ALDH1A1 (0.39) ALDH1A1GAAUSP2PKMHPGD
SCHEMBL6536206 0.79 ALOX15 (0.48) ALDH1A1GAAUSP2PKMHPGD
SCHEMBL20717781 0.79 ESR1 (0.54) ALDH1A1GAAUSP2PKMHPGD
SCHEMBL27988700 0.76 ABCB11 (0.42) TSHR
SCHEMBL8730421 0.76 ALDH1A1 (0.41) ALDH1A1GAAUSP2PKMHPGD
SCHEMBL1006801 0.76 HDAC4 (0.62) ALDH1A1GAAUSP2PKMHPGD
SCHEMBL198138 0.75 HDAC4 (0.56) ALDH1A1GAAUSP2PKMHPGD
SCHEMBL18951073 0.75 ALDH1A1 (0.41) ALDH1A1GAAUSP2PKMHPGD
SCHEMBL15445117 0.74 USP2 (0.44) ALDH1A1GAAUSP2PKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0856504-B1 Process for producing 3,3',5,5'-tetra-t-butylbiphenol HONSHU CHEMICAL IND (JP) 2001-11-07 EP disclosed
EP-0856504-A1 Process for producing 3,3',5,5'-tetra-t-butylbiphenol HONSHU CHEMICAL INDUSTRY CO. LTD. (JP) 1998-08-05 EP disclosed