Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558629 | 0.81 | NPSR1 (0.32) | ALDH1A1NPSR1SMN1; SMN2HSD17B10LMNA | |
| SCHEMBL467913 | 0.81 | NPSR1 (0.32) | ALDH1A1NPSR1SMN1; SMN2HSD17B10LMNA | |
| SCHEMBL329244 | 0.79 | ALDH1A1 (0.33) | ALDH1A1NPSR1HSD17B10LMNA | |
| SCHEMBL7788007 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TRPV1ACACBMTNR1AMTNR1B | |
| SCHEMBL7791576 | 0.76 | MTNR1A (0.36) | ALDH1A1TRPV1ACACBMTNR1AMTNR1B | |
| SCHEMBL3653028 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1ACACBSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL960688 | 0.71 | MMP1 (0.32) | ALDH1A1TRPV1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL177660 | 0.67 | — | — | |
| SCHEMBL6695758 | 0.66 | — | — | |
| SCHEMBL121148 | 0.65 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11071385-A | — | — | None | — | — | JP | disclosed |
| EP-0885895-B1 | N-[omega-(methyl),omega-(silyl)]alkyl-N-organocarboxamide, their oligomers and polycondensates, process for their preparation and their use | DEGUSSA (DE) | 2001-11-07 | — | — | EP | disclosed |
| US-6020448-A | N-[ω-(methyl),ω-(silyl)] alkyl-N-organocarboxamides, oligomeric and polycondensed Si-containing compounds thereof, processes for their preparation, and their use | HUELS AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |
| JP-H1171385-A | N-(OMEGA-(METHYL), OMEGA-(SILYL))ALKYL-N-ORGANO-CARBOXYAMIDE, SILICON-CONTAINING OLIGOMER AND POLYCONDENSATION PRODUCT, THEIR PRODUCTION AND USE | HUELS AG | 1999-03-16 | — | — | JP | disclosed |
| EP-0885895-A2 | N-[omega-(methyl),omega-(silyl)]alkyl-N-organocarboxamide, their oligomers and polycondensates, process for their preparation and their use | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-12-23 | — | — | EP | disclosed |