Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790240 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1GAAL3MBTL1LTA4H | |
| SCHEMBL952721 | 0.83 | LTA4H (0.63) | KDM4EALDH1A1LTA4HADRA1DADRA1A | |
| SCHEMBL19465330 | 0.83 | LTA4H (0.63) | KDM4EALDH1A1LTA4HADRA1DADRA1A | |
| SCHEMBL952722 | 0.83 | LTA4H (0.63) | KDM4EALDH1A1LTA4HADRA1DADRA1A | |
| SCHEMBL7781292 | 0.83 | CYP1A2 (0.50) | PRKG1PDCD1CD274SMN1; SMN2 | |
| SCHEMBL7781291 | 0.83 | CYP1A2 (0.50) | PRKG1PDCD1CD274SMN1; SMN2 | |
| SCHEMBL24434971 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1GAAL3MBTL1LTA4H | |
| SCHEMBL3143329 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1GAAL3MBTL1LTA4H | |
| SCHEMBL22453467 | 0.81 | LTA4H (0.52) | KDM4EALDH1A1GAAL3MBTL1LTA4H | |
| SCHEMBL15274471 | 0.80 | GRM2 (0.48) | KDM4EALDH1A1GAAL3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010056185-A1 | C3A receptor ligands | LEE DENNIS (US) | 2001-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056185-A1 | C3A receptor ligands | C3AR1, C5AR1, C5AR2 | KDM4E 4681/4885ALDH1A1 2838/4885GAA 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.