Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423315 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL4972944 | 0.88 | EPHX1 (0.52) | BTKEPHX1NPSR1NPC1RAB9A | |
| SCHEMBL10007376 | 0.86 | BTK (0.45) | BTKEPHX1NPSR1ALDH1A1EPHX2 | |
| SCHEMBL868764 | 0.86 | EPHX1 (0.59) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25699426 | 0.84 | BTK (0.41) | BTKEPHX1NPSR1KDM4EGRM5 | |
| SCHEMBL1067515 | 0.84 | EPHX1 (0.63) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17169490 | 0.84 | EPHX1 (0.63) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15700754 | 0.84 | EPHX1 (0.63) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8393998 | 0.84 | EPHX1 (0.63) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19426065 | 0.84 | EPHX1 (0.63) | EPHX1NPSR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927763-B2 | Method for preparing aliphatic diisocyanate | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2015-01-06 | — | — | US | claimed |
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2014-10-09 | — | — | US | claimed |
| US-8927763-B2 | Method for preparing aliphatic diisocyanate | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2015-01-06 | — | — | US | disclosed |
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2014-10-09 | — | — | US | disclosed |
| EP-0795544-B1 | Process for the thermal decomposition of carbamic esters | BAYER AG (DE) | 2001-10-31 | — | — | EP | disclosed |
| EP-0795543-B1 | Use of high boiling solvents or solvent mixtures as heat exchange medium in the thermal decomposition of carbamic esters | BAYER AG (DE) | 2001-10-31 | — | — | EP | disclosed |
| US-5883291-A | Heat exchange media for the thermal cracking of carbamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| US-5731458-A | Process for thermally cracking carbamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| EP-0795544-A1 | Process for the thermal decomposition of carbamic esters | BAYER AG (DE) | 1997-09-17 | — | — | EP | disclosed |
| EP-0795543-A1 | Use of high boiling solvents or solvent mixtures as heat exchange medium in the thermal decomposition of carbamic esters | BAYER AG (DE) | 1997-09-17 | — | — | EP | disclosed |
| EP-0542106-B1 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1995-12-27 | — | — | EP | disclosed |
| EP-0396977-B1 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| US-5284969-A | Thermal decomposition of the corresponding carbamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| EP-0542106-A2 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5138015-A | Reacting dialkyl carbonate with diamine to give urethane, thermally decomposing into diisocyanate, coverting into polyurethane in presence of Lewis acid and/or protonic acid | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0477376-A1 | PROCESS FOR PRODUCING POLYURETHANE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-5043471-A | Process for the preparation of polyisocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0396977-A2 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1990-11-14 | — | — | EP | disclosed |
| EP-0396976-A2 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1990-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | ALKBH3, DDC, ALKBH5 | BTK 2891/4885EPHX1 3411/4885NPSR1 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.