SCHEMBL28048938

SCHEMBL28048938

NN=C(C(=O)c1ccccc1)c1ccccc1.O=Cc1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.40
LMNA P02545 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
HDAC1 Q13547 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 2/20 0.38
USP2 O75604 1/20 0.38
POLB P06746 1/20 0.38
ALOX12 P18054 1/20 0.38
BLM P54132 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790426 0.80 CES2 (0.56) MAPTLMNAL3MBTL1ALDH1A1TDP1
SCHEMBL17485943 0.80 CES2 (0.56) MAPTLMNAL3MBTL1ALDH1A1TDP1
SCHEMBL28357767 0.80 MEN1 (0.42) MAPTALDH1A1HDAC8HDAC6MEN1
SCHEMBL28359736 0.73 ALDH1A1 (0.62) MAPTLMNAALDH1A1TDP1MEN1
SCHEMBL1509673 0.73 TDP1 (0.63) LMNAALDH1A1TDP1HDAC1HDAC8
SCHEMBL97422 0.73
SCHEMBL29815450 0.73
SCHEMBL7929793 0.73 CES2 (0.50) LMNACES2CES1MEN1KMT2A
Glycine SCHEMBL28033834 0.73 PTGDR2 (0.46) MAPTLMNAALDH1A1TDP1HDAC1
Methyl Alcohol SCHEMBL28778721 0.71 TDP1 (0.55) LMNAALDH1A1TDP1HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105348146-B Structure, preparation and use of benzil hydrazone-chlorobenzaldehyde bis-Schiff base 齐鲁工业大学 2017-02-22 CN disclosed
CN-105348146-A Structure, preparation and use of benzil hydrazone-chlorobenzaldehyde bis-Schiff base UNIV QILU TECHNOLOGY 2016-02-24 CN disclosed
CN-105348146-A Structure, preparation and use of benzil hydrazone-chlorobenzaldehyde bis-Schiff base UNIV QILU TECHNOLOGY 2016-02-24 CN disclosed
CN-105348146-A Structure, preparation and use of benzil hydrazone-chlorobenzaldehyde bis-Schiff base UNIV QILU TECHNOLOGY 2016-02-24 CN disclosed