SCHEMBL7790459

SCHEMBL7790459

Cc1ccc(C(=O)c2ccc(C)cc2S(=O)(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
LMNA P02545 3/20 0.50
AKR1C3 P42330 1/20 0.46
MAPT P10636 5/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
GAA P10253 1/20 0.45
SRD5A2 P31213 2/20 0.44
NPC1 O15118 3/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
CA2 P00918 1/20 0.42
RAB9A P51151 1/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21636268 0.89 CSNK2A1 (0.38) ALDH1A1LMNAMAPTL3MBTL1GAA
SCHEMBL21636265 0.87 ALDH1A1 (0.45) ALDH1A1LMNAMAPTGAANPC1
SCHEMBL780497 0.86 ALDH1A1 (0.50) ALDH1A1LMNAAKR1C3MAPTL3MBTL1
SCHEMBL11526907 0.84 MAPT (0.49) ALDH1A1LMNAAKR1C3MAPTL3MBTL1
SCHEMBL777167 0.83 AKR1C3 (0.59) ALDH1A1LMNAAKR1C3MAPTL3MBTL1
SCHEMBL2758534 0.80 MAPT (0.50) ALDH1A1LMNAMAPTNPC1MAPK1
SCHEMBL5706560 0.80 CSNK2A1 (0.50) ALDH1A1CA2KMT2ATDP1
SCHEMBL10068941 0.80 KDM4E (0.39) ALDH1A1LMNAMAPTL3MBTL1GAA
SCHEMBL27909908 0.79 CSNK2A1 (0.48) ALDH1A1KMT2ATDP1
SCHEMBL9856886 0.77 ALDH1A1 (0.62) ALDH1A1LMNAAKR1C3MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220226216-A1 HAIR TREATMENT METHOD KAO CORPORATION (JP) 2022-07-21 US disclosed
EP-3998060-A1 HAIR COSMETIC Kao Corporation (JP) 2022-05-18 EP disclosed
US-11234916-B2 Hair cosmetic KAO CORPORATION (JP) 2022-02-01 US disclosed
EP-3395323-B1 METHOD FOR TREATING HAIR KAO CORP (JP) 2021-09-29 EP disclosed
US-20210069081-A1 HAIR COSMETIC KAO CORPORATION (JP) 2021-03-11 US disclosed
EP-3741352-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 2020-11-25 EP disclosed
WO-2019142815-A1 HAIR COSMETIC COMPOSITION 花王株式会社 2019-07-25 WO disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 US disclosed
EP-3395323-A1 HAIR TREATMENT METHOD Kao Corporation (JP) 2018-10-31 EP disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 EP disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210069081-A1 HAIR COSMETIC TYR, CUTA, H1-0 ALDH1A1 494/4885LMNA 1395/4885AKR1C3 2468/4885
US-20220226216-A1 HAIR TREATMENT METHOD POLR1C, ALDH7A1, CA7 ALDH1A1 6/4885LMNA 1950/4885AKR1C3 69/4885
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 ALDH1A1 201/4885LMNA 2120/4885AKR1C3 239/4885
US-11234916-B2 Hair cosmetic TYR, CUTA, H1-0 ALDH1A1 494/4885LMNA 1395/4885AKR1C3 2468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.