Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 12/20 | 0.56 |
| ▸ | FDPS | P14324 | 5/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793553 | 0.83 | GRM5 (0.50) | PPIAGRM5LTA4HMAPK14 | |
| SCHEMBL12794086 | 0.79 | GRM5 (0.56) | PPIAGRM5LTA4HMAPK14 | |
| SCHEMBL20377249 | 0.77 | FDPS (0.56) | PPIAFDPSPTK2BGRM5 | |
| SCHEMBL8812159 | 0.74 | PPIA (0.54) | PPIAGRM5 | |
| SCHEMBL2655744 | 0.74 | LTA4H (0.63) | PPIAGRM5LTA4HMAPK14 | |
| SCHEMBL14647654 | 0.74 | GRM5 (0.60) | PPIAGRM5LTA4HMAPK14 | |
| SCHEMBL10424550 | 0.74 | PPIA (0.74) | PPIA | |
| SCHEMBL8032303 | 0.73 | PPIA (0.59) | PPIAGRM5LTA4HMAPK14 | |
| SCHEMBL20604564 | 0.73 | PPIA (0.59) | PPIAGRM5LTA4HMAPK14 | |
| SCHEMBL15163926 | 0.73 | FDPS (0.61) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |