Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | PPIA | P62937 | 16/20 | 0.49 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | PPIF | P30405 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790466 | 0.83 | PPIA (0.56) | GRM5PPIALTA4HMAPK14 | |
| SCHEMBL8166679 | 0.78 | FDPS (0.62) | — | |
| SCHEMBL12794086 | 0.78 | GRM5 (0.56) | GRM5PPIAGCKPPIFLTA4H | |
| SCHEMBL5155756 | 0.77 | FDPS (0.47) | — | |
| SCHEMBL8410675 | 0.76 | FFAR1 (0.46) | LTA4H | |
| SCHEMBL7784728 | 0.74 | NPC1 (0.49) | — | |
| SCHEMBL7793618 | 0.74 | P4HTM (0.47) | GCKLTA4H | |
| SCHEMBL14647654 | 0.73 | GRM5 (0.60) | GRM5PPIAGCKPPIFLTA4H | |
| SCHEMBL5360999 | 0.72 | FDPS (0.58) | GRM5 | |
| SCHEMBL20628184 | 0.72 | PPIA (0.55) | GRM5PPIAGCKLTA4HMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |
| EP-0762883-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033466-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1995-12-14 | — | — | WO | claimed |
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | disclosed |
| US-6083938-A | TREATING BONE DISEASES SELECTED FROM THE GROUP CONSISTING OF OSTEOLYTIC BONE DISEASES DUE TO MALIGNANCY, PAGET'S DISEASE AND PRIMARY AND SECONDARY OSTEOPOROSIS | LEIRAS OY (FI) | 2000-07-04 | — | — | US | disclosed |
| US-5866556-A | BONE DISORDERS | LEIRAS OY (FI) | 1999-02-02 | — | — | US | disclosed |
| EP-0762883-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033466-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1995-12-14 | — | — | WO | disclosed |