Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15993621 | 0.95 | LMNA (0.54) | LMNATDP1ALDH1A1CYP3A4CA2 | |
| SCHEMBL17417899 | 0.93 | LMNA (0.53) | LMNATDP1ALDH1A1CYP3A4CA2 | |
| SCHEMBL19614688 | 0.86 | TDP1 (0.49) | LMNATDP1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL1650196 | 0.86 | TDP1 (0.49) | LMNATDP1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL23398209 | 0.83 | LMNA (0.64) | LMNATDP1ALDH1A1CYP3A4CA2 | |
| SCHEMBL28962981 | 0.82 | TDP1 (0.44) | LMNATDP1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11403740 | 0.81 | LMNA (0.50) | LMNATDP1ALDH1A1CYP3A4CA2 | |
| SCHEMBL186936 | 0.81 | LMNA (0.50) | LMNATDP1ALDH1A1CYP3A4CA2 | |
| SCHEMBL5606092 | 0.80 | TDP1 (0.43) | LMNATDP1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6896518 | 0.80 | TDP1 (0.50) | LMNATDP1ALDH1A1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150718-A1 | CONJUGATES OF LIPIDS AND ANTIMICROBIAL OR ANTINEOPLASTIC DRUGS | OREGON HEALTH SCIENCES UNIVERSITY (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000033883-A1 | COVALENT POLAR LIPID CONJUGATES WITH ANTIMICROBIAL AND ANTINEOPLASTIC DRUGS FOR TARGETING TO BIOLOGICAL PROTECTED SITES | OREGON HEALTH SCIENCES UNIVERSITY (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000033884-A1 | CONJUGATES OF LIPIDS AND ANTIMICROBIAL OR ANTINEOPLASTIC DRUGS | OREGON HEALTH SCIENCES UNIVERSITY (US) | 2000-06-15 | — | — | WO | disclosed |