Sugi Predict

Sugi Predict / Compounds / SCHEMBL17417899

SCHEMBL17417899

SCHEMBL17417899

CCCCCCC(N)C(=O)OC(=O)c1ccccc1O.[NaH]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.53
▸ PRSS1 P07477 1/20 0.49
▸ PRSS2 P07478 1/20 0.49
▸ PRSS3 P35030 1/20 0.49
▸ ALDH1A1 P00352 5/20 0.47
▸ TSHR P16473 4/20 0.47
▸ NAAA Q02083 1/20 0.46
▸ TDP1 Q9NUW8 3/20 0.46
▸ HSD17B10 Q99714 2/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ POLB P06746 1/20 0.45
▸ CYP3A4 P08684 3/20 0.44
▸ TP53 P04637 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ MEN1 O00255 1/20 0.40
▸ NR1I2 O75469 1/20 0.40
▸ CHRM2 P08172 1/20 0.40
▸ ADRA2A P08913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15993621 0.99 LMNA (0.54) LMNAPRSS1PRSS2PRSS3ALDH1A1
SCHEMBL7790573 0.93 LMNA (0.60) LMNAPRSS1PRSS2PRSS3ALDH1A1
SCHEMBL1650196 0.85 TDP1 (0.49) LMNAALDH1A1TSHRTDP1HSD17B10
SCHEMBL19614688 0.85 TDP1 (0.49) LMNAALDH1A1TSHRTDP1HSD17B10
SCHEMBL17821459 0.81 LMNA (0.47) LMNAPRSS1PRSS2PRSS3ALDH1A1
SCHEMBL7571356 0.80 ALDH1A1 (0.54) LMNAPRSS1PRSS2PRSS3ALDH1A1
SCHEMBL28867197 0.80 ALDH1A1 (0.54) LMNAPRSS1PRSS2PRSS3ALDH1A1
SCHEMBL2812100 0.80 ALDH1A1 (0.54) LMNAPRSS1PRSS2PRSS3ALDH1A1
Salicylic Acid SCHEMBL28307845 0.79 ALDH1A1 (0.50) LMNAPRSS1PRSS2PRSS3ALDH1A1
SCHEMBL28962981 0.79 TDP1 (0.44) LMNAALDH1A1TSHRNAAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240009157-A1 3,5-DIIODOTHYROPROPIONIC ACID COMPOSITIONS AND METHODS OF USE THEREOF DEXCEL PHARMA TECHNOLOGIES LTD. (IL) 2024-01-11 — — US claimed
EP-3277283-B1 SILDENAFIL SUBLINGUAL SPRAY FORMULATIONS FRESH CUT DEV LLC (US) 2021-03-03 — — EP claimed
EP-3612173-A1 EPINEPHRINE SPRAY FORMULATIONS Hikma Pharmaceuticals USA Inc. (US) 2020-02-26 — — EP claimed
US-10111833-B2 Sildenafil sublingual spray formulations INSYS DEVELOPMENT COMPANY, INC. (US) 2018-10-30 — — US claimed
WO-2018195029-A1 EPINEPHRINE SPRAY FORMULATIONS INSYS DEVELOPMENT COMPANY, INC. (US) 2018-10-25 — — WO claimed
US-10039710-B2 Epinephrine spray formulations INSYS DEVELOPMENT COMPANY, INC. (US) 2018-08-07 — — US claimed
EP-3277283-A1 SILDENAFIL SUBLINGUAL SPRAY FORMULATIONS Insys Development Company, Inc. (US) 2018-02-07 — — EP claimed
US-20170216199-A1 EPINEPHRINE SPRAY FORMULATIONS HIKMA PHARMACEUTICALS USA INC. 2017-08-03 — — US claimed
US-20170216196-A1 SILDENAFIL SUBLINGUAL SPRAY FORMULATIONS BENUVIA OPERATIONS, LLC 2017-08-03 — — US claimed
US-9662334-B2 Sildenafil sublingual spray formulations INSYS DEVELOPMENT COMPANY, INC. (US) 2017-05-30 — — US claimed
US-20160354363-A1 LIQUID NALOXONE SPRAY HIKMA PHARMACEUTICALS USA INC. 2016-12-08 — — US claimed
WO-2016161397-A1 SILDENAFIL SUBLINGUAL SPRAY FORMULATIONS INSYS DEVELOPMENT COMPANY, INC. (US) 2016-10-06 — — WO claimed
US-20160287593-A1 SILDENAFIL SUBLINGUAL SPRAY FORMULATIONS BENUVIA OPERATIONS, LLC 2016-10-06 — — US claimed
US-20160199294-A1 SUBLINGUAL NALOXONE SPRAY HIKMA PHARMACEUTICALS USA INC. 2016-07-14 — — US claimed
US-20240165191-A1 COMPOSITIONS AND METHODS FOR REDUCING THE TRANSMISSIVITY OF ILLNESSES USING AN ORAL DELIVERY SYSTEM LORENZEN LEE H (US) 2024-05-23 — — US disclosed
US-11975096-B2 Liquid naloxone spray HIKMA PHARMACEUTICALS USA INC. (US) 2024-05-07 — — US disclosed
US-11918655-B2 Intranasal epinephrine formulations and methods for the treatment of disease AEGIS THERAPEUTICS, LLC (US) 2024-03-05 — — US disclosed
US-20160199294-A1 SUBLINGUAL NALOXONE SPRAY HIKMA PHARMACEUTICALS USA INC. 2016-07-14 — — US disclosed
US-20160008349-A1 SUBLINGUAL NALOXONE SPRAY INSYS DEVELOPMENT COMPANY, INC. 2016-01-14 — — US disclosed
WO-2016007245-A1 SUBLINGUAL NALOXONE SPRAY INSYS PHARMA, INC. (US) 2016-01-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170216199-A1 EPINEPHRINE SPRAY FORMULATIONS ADRA2C, ADRB3, ADRB2 LMNA 4469/4885PRSS1 824/4885PRSS2 1263/4885
US-11918655-B2 Intranasal epinephrine formulations and methods for the treatment of disease ADRA2C, ADRA2A, ADRB2 LMNA 2042/4885PRSS1 976/4885PRSS2 1215/4885
US-11975096-B2 Liquid naloxone spray OPRL1, OPRK1, OPRD1 LMNA 4139/4885PRSS1 1448/4885PRSS2 1885/4885
US-10039710-B2 Epinephrine spray formulations ADRA2C, ADRB3, ADRB2 LMNA 4469/4885PRSS1 824/4885PRSS2 1263/4885
US-20160008349-A1 SUBLINGUAL NALOXONE SPRAY OPRL1, OPRK1, SLC6A3 LMNA 4343/4885PRSS1 1205/4885PRSS2 1600/4885
US-20160354363-A1 LIQUID NALOXONE SPRAY OPRL1, OPRK1, OPRD1 LMNA 4216/4885PRSS1 1173/4885PRSS2 1541/4885
US-20160199294-A1 SUBLINGUAL NALOXONE SPRAY OPRL1, OPRK1, SLC6A3 LMNA 4343/4885PRSS1 1205/4885PRSS2 1600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.