Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3483347 | 0.80 | KDM4E (0.50) | CES2CES1ALDH1A1KDM4EMEN1 | |
| SCHEMBL5748794 | 0.79 | LCK (0.56) | CES2CES1LCKALDH1A1KDM4E | |
| SCHEMBL15711096 | 0.79 | CYP2A6 (0.50) | CES2CES1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11674987 | 0.76 | CES2 (0.44) | CES2CES1LCKALDH1A1KDM4E | |
| SCHEMBL8733472 | 0.76 | CES2 (0.63) | CES2CES1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5553792 | 0.75 | RAB9A (0.60) | CES2CES1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6606896 | 0.75 | PLAU (0.57) | SMN1; SMN2HPGDCYP3A4 | |
| SCHEMBL2899731 | 0.75 | PTPN11 (0.53) | LCKALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6631674 | 0.73 | KDM4E (0.46) | CES2CES1ALDH1A1KDM4EMEN1 | |
| SCHEMBL5748538 | 0.72 | LCK (0.58) | CES2CES1LCKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962627-A | MECHANICAL PROPERTIES; ADHESIVES | AKZO NOBEL N.V. (NL) | 1999-10-05 | — | — | US | claimed |
| EP-1148934-A1 | MEMBRANE FOR SEPARATION OF XENON FROM OXYGEN AND NITROGEN AND METHOD OF USING SAME | MESSER GRIESHEIM GMBH (DE) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000033949-A1 | MEMBRANE FOR SEPARATION OF XENON FROM OXYGEN AND NITROGEN AND METHOD OF USING SAME | MESSER GRIESHEIM GMBH (DE) | 2000-06-15 | — | — | WO | disclosed |
| US-4608429-A | Low-melting aromatic polyesters with repeating 2,2'-substituted-biphenylene radicals | POLAROID CORPORATION, PATENT DEPT. (US) | 1986-08-26 | — | — | US | disclosed |