SCHEMBL7790907

SCHEMBL7790907

[c]1nccc2c1cnc1cnccc12

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 1/20 0.40
KDM4B O94953 1/20 0.40
KDM5C P41229 1/20 0.40
KDM4C Q9H3R0 1/20 0.40
KDM5B Q9UGL1 1/20 0.40
KDM3A Q9Y4C1 1/20 0.40
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HTT P42858 1/20 0.35
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
LATS1 O95835 4/20 0.33
LATS2 Q9NRM7 3/20 0.33
EGFR P00533 2/20 0.33
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17511873 0.72 IMPDH2 (0.42) KDM4EALDH1A1HTTNCOA1NCOA3
SCHEMBL25836 0.70 CLK1 (0.42) KDM4EHTTNCOA3
SCHEMBL8067522 0.70 KDM4E (0.63) KDM4AKDM4BKDM5CKDM4CKDM5B
SCHEMBL158554 0.67 CLK1 (0.33) KDM4EHTT
SCHEMBL855569 0.67 EGFR (0.32) KDM4AKDM4BKDM5CKDM4CKDM5B
SCHEMBL17511951 0.67 MAPT (0.59) KDM4EALDH1A1HTTNCOA1NCOA3
SCHEMBL15578212 0.67 KDM4E (0.39) KDM4CKDM4EALDH1A1HTTACHE
SCHEMBL15578381 0.67 KDM4E (0.39) KDM4AKDM4BKDM5CKDM4CKDM5B
SCHEMBL159538 0.66 PRKCZ (0.33) KDM4E
SCHEMBL2407348 0.65 KDM4E (0.67) KDM4AKDM4BKDM5CKDM4CKDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed