Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | SNCA | P37840 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87790 | 0.80 | GAA (0.47) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL17363539 | 0.76 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL563959 | 0.75 | GAA (0.42) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL2536442 | 0.75 | NOX1 (0.48) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL433232 | 0.74 | NOX1 (0.42) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL2504207 | 0.71 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL29352248 | 0.71 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL29349533 | 0.71 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL9114 | 0.71 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL6315328 | 0.71 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704535-B1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | BAYER AG (US) | 2001-11-28 | — | — | EP | claimed |
| EP-0704535-A2 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1996-04-03 | — | — | EP | claimed |
| US-5498542-A | Electrode mediators for regeneration of NADH and NADPH | BAYER CORPORATION (US) | 1996-03-12 | — | — | US | claimed |
| JP-8100284-A | — | — | None | — | — | JP | disclosed |
| EP-0704535-B1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | BAYER AG (US) | 2001-11-28 | — | — | EP | disclosed |
| JP-H08100284-A | MEDIATOR FOR ELECTROCHEMICAL REGENERATION OF NADH, NADPH OR THEIR ANALOGUE | BAYER CORP | 1996-04-16 | — | — | JP | disclosed |
| EP-0704535-A2 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0704535-A2 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5498542-A | Electrode mediators for regeneration of NADH and NADPH | BAYER CORPORATION (US) | 1996-03-12 | — | — | US | disclosed |
| US-5498542-A | Electrode mediators for regeneration of NADH and NADPH | BAYER CORPORATION (US) | 1996-03-12 | — | — | US | disclosed |