SCHEMBL563959

SCHEMBL563959

C1=CC2=C(CC1=Nc1ccccc1)Sc1ccccc1N2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 8/20 0.42
▸ MAPT P10636 8/20 0.42
▸ NOX1 Q9Y5S8 6/20 0.42
▸ MEN1 O00255 6/20 0.42
▸ KMT2A Q03164 6/20 0.42
▸ BCHE P06276 2/20 0.42
▸ ACHE P22303 2/20 0.42
▸ ALOX12 P18054 2/20 0.42
▸ CYP1A2 P05177 2/20 0.42
▸ CYP3A4 P08684 2/20 0.42
▸ TDP1 Q9NUW8 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ ADORA3 P0DMS8 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ MAOA P21397 1/20 0.42
▸ CNR1 P21554 1/20 0.42
▸ PTGS1 P23219 1/20 0.42
▸ SLC6A2 P23975 1/20 0.42
▸ HTR2C P28335 1/20 0.42
▸ PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433232 0.89 NOX1 (0.42) GAAMAPTNOX1MEN1KMT2A
SCHEMBL436033 0.87 NOX1 (0.41) GAAMAPTNOX1MEN1KMT2A
SCHEMBL433635 0.86 MAPT (0.39) GAAMAPTNOX1MEN1KMT2A
SCHEMBL435356 0.86 NOX1 (0.35) GAAMAPTNOX1MEN1KMT2A
SCHEMBL434961 0.86 NOX1 (0.46) GAAMAPTNOX1MEN1KMT2A
SCHEMBL434466 0.86 MAPT (0.46) GAAMAPTNOX1MEN1KMT2A
SCHEMBL436040 0.84 NOX1 (0.38) GAAMAPTNOX1MEN1KMT2A
SCHEMBL563322 0.84 NOX1 (0.38) GAAMAPTNOX1MEN1KMT2A
SCHEMBL434444 0.84 NOX1 (0.36) GAAMAPTNOX1MEN1KMT2A
SCHEMBL434952 0.84 SNCA (0.48) GAAMAPTNOX1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11442035-B2 Electrochemical test sensor ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2022-09-13 — — US claimed
EP-3543348-B1 BIOSENSOR SYSTEM HAVING ENHANCED STABILITY AND HEMATOCRIT PERFORMANCE ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2020-11-18 — — EP claimed
US-10457971-B2 Method of making an electrochemical sensor strip ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2019-10-29 — — US claimed
EP-3543348-A1 BIOSENSOR SYSTEM HAVING ENHANCED STABILITY AND HEMATOCRIT PERFORMANCE Ascensia Diabetes Care Holdings AG (CH) 2019-09-25 — — EP claimed
EP-2089531-B1 BIOSENSOR SYSTEM HAVING ENHANCED STABILITY AND HEMATOCRIT PERFORMANCE ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2019-07-10 — — EP claimed
US-10329684-B2 Method for forming an optical test sensor ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2019-06-25 — — US claimed
EP-3187866-B1 ELECTROCHEMICAL TEST SENSOR ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2019-04-17 — — EP claimed
EP-2229590-B1 PROCESS OF MAKING 3-PHENYLIMINO-3H-PHENOTHIAZINE OR 3-PHENYLIMINO-3H-PHENOXAZINE MEDIATOR ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2018-11-21 — — EP claimed
US-20180059042-A1 Electrochemical Test Sensor BAYER HEALTHCARE LLC 2018-03-01 — — US claimed
US-20180016615-A1 METHOD OF MAKING AN ELECTROCHEMICAL SENSOR STRIP BAYER HEALTHCARE LLC 2018-01-18 — — US claimed
WO-2005078118-A1 OXIDIZABLE SPECIES AS AN INTERNAL REFERENCE FOR BIOSENSORS AND METHOD OF USE BAYER HEALTHCARE LLC (US) 2005-08-25 — — WO claimed
WO-2005040407-A1 ENZYMATIC ELECTROCHEMICAL BIOSENSOR BAYER HEALTHCARE LLC (US) 2005-05-06 — — WO claimed
US-20040185517-A1 Method and test strip for determining glucose in blood ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2004-09-23 — — US claimed
CN-1527045-A Method for measuring glucose in blood and test strap 拜尔健康护理有限责任公司 2004-09-08 — — CN claimed
EP-1445329-A2 Method and test strip for determining glucose in blood Bayer Healthcare, LLC (US) 2004-08-11 — — EP claimed
EP-0747984-B1 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof BAYER AG (US) 2002-08-14 — — EP claimed
EP-0775699-A1 Method for the preparation of substituted 3-(phenylimino)-3H-phenothiazines and phenoxazines Bayer Corporation (US) 1997-05-28 — — EP claimed
US-5631371-A Method for the preparation of substituted 3-(phenylimino)-3H-phenothiazines and phenoxazines BAYER CORPORATION (US) 1997-05-20 — — US claimed
EP-0747984-A2 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof Bayer Corporation (US) 1996-12-11 — — EP claimed
US-5520786-A ELECTRODE SURFACE HAS BEEN IMPARTED BY A MEDIATOR FUNCTION COMPRISING ONE OR MORE MEDIATOR COMPOUNDS SELECTED FROM SUBSTITUTED OR UNSUBSTITUTED 3-PHENYLIMINO-3H-PHENOTHIAZINES AND 3-PHENYLIMINO-3H-PHENOXAZINES BAYER CORPORATION (US) 1996-05-28 — — US claimed
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