Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SNCA | P37840 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591086 | 0.81 | NOX1 (0.50) | GAAMAPTNOX1KMT2ASNCA | |
| SCHEMBL12812969 | 0.80 | CA9 (0.33) | GAAMAPTNOX1MEN1KMT2A | |
| SCHEMBL10591877 | 0.80 | EPHX2 (0.48) | GAAMAPTNOX1MEN1KMT2A | |
| SCHEMBL7790923 | 0.80 | NOX1 (0.52) | GAAMAPTNOX1MEN1KMT2A | |
| SCHEMBL16061005 | 0.78 | NOX1 (0.43) | GAAMAPTNOX1KMT2AALOX15 | |
| SCHEMBL10591060 | 0.77 | SNCA (0.55) | GAAMAPTNOX1MEN1KMT2A | |
| SCHEMBL3112042 | 0.77 | MAPT (0.36) | GAAMAPTNOX1MEN1KMT2A | |
| SCHEMBL17363539 | 0.76 | NOX1 (0.43) | GAAMAPTNOX1MEN1KMT2A | |
| SCHEMBL563959 | 0.75 | GAA (0.42) | GAAMAPTNOX1MEN1KMT2A | |
| SCHEMBL12272774 | 0.75 | ALDH1A1 (0.34) | GAAMAPTMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 748 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190023738-A1 | THERAPEUTIC COMPOSITIONS INCLUDING PHENAZINE-3-ONE AND PHENOTHIAZINE-3-ONE DERIVATIVES AND USES THEREOF | STEALTH PEPTIDES INTERNATIONAL, INC. (MC) | 2019-01-24 | — | — | US | claimed |
| US-20160228491-A1 | THERAPEUTIC COMPOSITIONS INCLUDING PHENAZINE-3-ONE AND PHENOTHIAZINE-3-ONE DERIVATIVES AND USES THEREOF | STEALTH PEPTIDES INTERNATIONAL, INC. (MC) | 2016-08-11 | — | — | US | claimed |
| EP-2000451-B1 | METHOD OF INHIBITING POLYMERIZATION OF AROMATIC VINYL COMPOUND | HAKUTO KK (JP) | 2016-03-23 | — | — | EP | claimed |
| US-20120264985-A1 | PROCESS FOR INHIBITING POLYMERIZATION OF AN AROMATIC VINYL COMPOUND | HAKUTO CO., LTD. | 2012-10-18 | — | — | US | claimed |
| EP-2492268-A1 | Compounds having CRTH2 antagonist activity | Oxagen Limited (GB) | 2012-08-29 | — | — | EP | claimed |
| EP-2046740-B1 | COMPOUNDS HAVING CRTH2 ANTAGONIST ACTIVITY | OXAGEN LTD (GB) | 2012-05-23 | — | — | EP | claimed |
| EP-1343769-B1 | BENZOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 2010-08-04 | — | — | EP | claimed |
| US-20100166698-A1 | NEW COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2010-07-01 | — | — | US | claimed |
| EP-1511737-B1 | ARYLOXIMES | MERCK PATENT GMBH (DE) | 2010-02-17 | — | — | EP | claimed |
| EP-1509506-B1 | PYRIDAZINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-08-05 | — | — | EP | claimed |
| US-20020111495-A1 | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes | PFIZER INC. | 2002-08-15 | — | — | US | claimed |
| WO-2002060875-A1 | NICOTINAMIDE BIARYL DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | PFIZER PRODUCTS INC. (US) | 2002-08-08 | — | — | WO | claimed |
| WO-2002060896-A1 | ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | PFIZER PRODUCTS INC. (US) | 2002-08-08 | — | — | WO | claimed |
| EP-1229034-A1 | Nicotinamide derivatives and their mimetics as inhibitors of PDE4 isozymes | Pfizer Products Inc. (US) | 2002-08-07 | — | — | EP | claimed |
| WO-2002051814-A1 | BENZOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 2002-07-04 | — | — | WO | claimed |
| WO-2001057025-A1 | PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | PFIZER PRODUCTS INC. (US) | 2001-08-09 | — | — | WO | claimed |
| US-5500760-A | Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same | DONNELLY CORPORATION (US) | 1996-03-19 | — | — | US | claimed |
| EP-0531143-A2 | Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same | DONNELLY CORPORATION (US) | 1993-03-10 | — | — | EP | claimed |
| EP-0149297-B1 | PROCESS FOR PREPARING 3H-PHENOTHLAZIN-3-ONES | MERCK FROSST CANADA INC. (CA) | 1987-11-25 | — | — | EP | claimed |
| EP-0149297-A1 | Process for preparing 3H-Phenothlazin-3-ones | MERCK FROSST CANADA INC. (CA) | 1985-07-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166698-A1 | NEW COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | ADORA2A, ADORA2B, ADORA3 | GAA 3996/4885MAPT 4209/4885NOX1 724/4885 |
| US-20120264985-A1 | PROCESS FOR INHIBITING POLYMERIZATION OF AN AROMATIC VINYL COMPOUND | VCP, PAH, DDC | GAA 1301/4885MAPT 557/4885NOX1 1770/4885 |
| US-20160228491-A1 | THERAPEUTIC COMPOSITIONS INCLUDING PHENAZINE-3-ONE AND PHENOTHIAZINE-3-ONE DERIVATIVES AND USES THEREOF | TYR, DNPEP, ARG2 | GAA 1344/4885MAPT 76/4885NOX1 3272/4885 |
| US-20020111495-A1 | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes | NOX3, NOX1, NOX4 | GAA 743/4885MAPT 4775/4885NOX1 2/4885 |
| US-20190023738-A1 | THERAPEUTIC COMPOSITIONS INCLUDING PHENAZINE-3-ONE AND PHENOTHIAZINE-3-ONE DERIVATIVES AND USES THEREOF | TYR, DNPEP, ARG2 | GAA 1344/4885MAPT 76/4885NOX1 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.