Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789727 | 0.84 | TP53 (0.44) | KEAP1SLC5A2TSHRSLC5A1SLC6A2 | |
| SCHEMBL7781951 | 0.83 | CALM1 (0.50) | IDO1KEAP1CYP3A4SMN1; SMN2HTR2A | |
| SCHEMBL9403954 | 0.83 | SLC6A2 (0.47) | IDO1POLBKEAP1SLC5A2CYP3A4 | |
| SCHEMBL6378299 | 0.79 | POLB (0.51) | IDO1POLBKEAP1SLC5A2CYP3A4 | |
| SCHEMBL2140027 | 0.79 | HTR2A (0.54) | POLBCYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL16153738 | 0.78 | TAAR1 (0.47) | IDO1POLBKEAP1CYP3A4CYP2D6 | |
| SCHEMBL7791011 | 0.77 | CYP3A4 (0.45) | CYP3A4CYP2D6TSHRCYP2C19NPC1 | |
| SCHEMBL6547993 | 0.75 | POLB (0.45) | IDO1POLBKEAP1SLC5A2HSP90AA1 | |
| SCHEMBL5000663 | 0.73 | POLB (0.44) | IDO1POLBKEAP1SLC5A2HSP90AA1 | |
| SCHEMBL11658684 | 0.73 | POLB (0.44) | IDO1POLBKEAP1SLC5A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814095-B1 | Process for producing a shaped product | MENICON CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5866047-A | Process for producing a shaped product | MENICON CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0814095-A2 | Process for producing a shaped product | Menicon Co., Ltd. (JP) | 1997-12-29 | — | — | EP | disclosed |