SCHEMBL6547993

SCHEMBL6547993

CCc1ccccc1Cc1ccc(C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
HTR2A P28223 1/20 0.41
KEAP1 Q14145 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41
STAT3 P40763 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8093837 0.91 SLC6A4 (0.47) TSHRSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL9403954 0.91 SLC6A2 (0.47) POLBCYP3A4CYP2D6TSHRCYP2C19
SCHEMBL8095786 0.87 LTA4H (0.46) POLBSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL2140027 0.86 HTR2A (0.54) POLBCYP3A4CYP2D6TSHRCYP2C19
SCHEMBL8086923 0.84 CALM1 (0.55) TSHRSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL6548117 0.84 HTR2A (0.56) TSHRHTR2ALMNAL3MBTL1
SCHEMBL6546450 0.83 GABRA1 (0.40) POLBTSHRSMN1; SMN2MEN1KMT2A
SCHEMBL6546751 0.83 HTR2A (0.47) POLBCYP3A4CYP2D6TSHRCYP2C19
SCHEMBL8096061 0.83 LTA4H (0.46) CYP3A4CYP2D6TSHRCYP2C19SLC6A2
SCHEMBL6378299 0.82 POLB (0.51) POLBCYP3A4CYP2D6TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed