Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.42 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782009 | 0.84 | MAPT (0.53) | KDM4ELCKRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL7789707 | 0.83 | BACE1 (0.40) | NR4A2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6172886 | 0.82 | NR4A2 (0.51) | NR4A2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2964316 | 0.74 | NPC1 (0.54) | NR4A2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12641829 | 0.74 | NPC1 (0.54) | NR4A2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL26882759 | 0.73 | KDM4E (0.57) | NR4A2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7786715 | 0.73 | MAPT (0.53) | KDM4ELCKRAB9ACA1CA2 | |
| SCHEMBL2237855 | 0.73 | MTNR1A (0.56) | NR4A2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28655389 | 0.73 | PLA2G2A (0.55) | NR4A2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9039778 | 0.72 | MTNR1A (0.52) | NR4A2KDM4ECYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801750-B1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG IND OHIO INC (US) | 2001-11-07 | — | — | EP | disclosed |
| US-5514817-A | PHOTOCHROMIC | PPG INDUSTRIES, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1996004576-A1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES, INC. (US) | 1996-02-15 | — | — | WO | disclosed |