Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethylaminoethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249184 | 0.86 | MAPT (0.38) | MAPTALDH1A1SMN1; SMN2 | |
| Dimethylaminoethanol SCHEMBL1131844 | 0.85 | MAPT (0.71) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| Dimethylaminoethanol SCHEMBL1131385 | 0.85 | MAPT (0.71) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| Trolamine SCHEMBL37853 | 0.83 | MAPT (0.33) | MAPTSMN1; SMN2 | |
| Dimethylaminoethanol SCHEMBL1131908 | 0.82 | MAPT (0.67) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28211943 | 0.81 | CA1 (0.39) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2730430 | 0.80 | MAPT (0.33) | MAPT | |
| Trolamine SCHEMBL11787722 | 0.79 | CA1 (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL28672601 | 0.79 | MAPT (0.34) | MAPTSMN1; SMN2 | |
| Water SCHEMBL16611311 | 0.79 | MAPT (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105674-B | Granular laundry softening and washing additive | 宝洁公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-111433339-B | Granular laundry softening detergent additive | 宝洁公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-111417710-B | Method for treating an article of clothing | 宝洁公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-111417708-B | Granular laundry softening detergent additive | 宝洁公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-111406103-B | Granular laundry softening detergent additive | 宝洁公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-111417711-B | Granular laundry softening and refreshing detergent additive | 宝洁公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113481063-A | Granular laundry softening detergent additive | 宝洁公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-111417706-B | Granular laundry softening detergent additive | 宝洁公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-113166681-A | Granular laundry softening detergent additive | 宝洁公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112955530-A | Granular laundry softening detergent additive | 宝洁公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-111417710-A | Method for treating an article of clothing | 宝洁公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-111417706-A | Granular laundry softening detergent additive | 宝洁公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-111417708-A | Granular laundry softening detergent additive | 宝洁公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-111406103-A | Granular laundry softening detergent additive | 宝洁公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-105695160-B | Bis-azo colorant as blueing agent | 宝洁公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-104334701-A | Perfume composition | KAO CORP | 2015-02-04 | — | — | CN | disclosed |
| CN-1701114-A | fabric care compositions for lipophilic fluid systems | PROCTER & GAMBLE (US) | 2005-11-23 | — | — | CN | disclosed |
| CN-1332787-A | fabric care compositions and methods | PROCTER & GAMBLE (US) | 2002-01-23 | — | — | CN | disclosed |
| EP-1154068-A1 | SOFTENER COMPOSITION | Kao Corporation (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-1154067-A1 | SOFTENER COMPOSITION | Kao Corporation (JP) | 2001-11-14 | — | — | EP | disclosed |