Dimethylaminoethanol

Dimethylaminoethanol

SCHEMBL1131908

CN(C)CCO.CS(=O)(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of Dimethylaminoethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 1/20 0.31
MAPT P10636 1/20 0.67
ALDH1A1 P00352 2/20 0.41
PAOX Q6QHF9 1/20 0.38
GSR P00390 2/20 0.34
CA2 P00918 4/20 0.33
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
PRMT3 O60678 1/20 0.33
CARM1 Q86X55 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
PRMT1 Q99873 1/20 0.33
PRMT8 Q9NR22 1/20 0.33
ALOX15 P16050 1/20 0.32
CA1 P00915 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 2/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylaminoethanol SCHEMBL1131385 0.92 MAPT (0.71) MAPTALDH1A1PAOXGSRCA2
Dimethylaminoethanol SCHEMBL1131844 0.92 MAPT (0.71) MAPTALDH1A1PAOXGSRCA2
SCHEMBL28390474 0.83 MAPT (0.43) MAPTALDH1A1CA2CA12CA9
Dimethylaminoethanol SCHEMBL7791043 0.82 MAPT (0.57) MAPTALDH1A1PAOXCHRM2CHRM4
Dimethylaminoethanol SCHEMBL16756236 0.82
Dimethylaminoethanol SCHEMBL2149038 0.82 MAPT (1.00) MAPTALDH1A1PAOXCA2CA12
Dimethylaminoethanol SCHEMBL13169672 0.82
Dimethylaminoethanol SCHEMBL5945 0.82
Trifluoromethanesulfonic Acid SCHEMBL1131469 0.80 MAPT (0.55) MAPTALDH1A1
Trolamine SCHEMBL9827519 0.80 MAPT (0.38) MAPTALDH1A1CA2ALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4371653-A1 FABRICATION OF FILTRATION MEMBRANES Trustees of Tufts College (US) 2024-05-22 EP claimed
US-20200317976-A1 NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE MONASH UNIVERSITY (AU) 2020-10-08 US claimed
EP-3535049-A1 FABRICATION OF FILTRATION MEMBRANES Trustees Of Tufts College (US) 2019-09-11 EP claimed
US-20190262781-A1 FABRICATION OF FILTRATION MEMBRANES TRUSTEES OF TUFTS COLLEGE 2019-08-29 US claimed
EP-3458539-A1 NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE Monash University (AU) 2019-03-27 EP claimed
WO-2017197438-A1 NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE MONASH UNIVERSITY (AU) 2017-11-23 WO claimed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US claimed
EP-1805131-B1 IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS INNOVIA FILMS LTD (GB) 2011-02-16 EP claimed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed
US-12233383-B2 Fabrication of filtration membranes TRUSTEES OF TUFTS COLLEGE (US) 2025-02-25 US disclosed
EP-4371653-A1 FABRICATION OF FILTRATION MEMBRANES Trustees of Tufts College (US) 2024-05-22 EP disclosed
US-20240149225-A1 FABRICATION OF FILTRATION MEMBRANES TRUSTEES OF TUFTS COLLEGE 2024-05-09 US disclosed
US-11896937-B2 Fabrication of filtration membranes TRUSTEES OF TUFTS COLLEGE (US) 2024-02-13 US disclosed
WO-2023168258-A2 ELECTROCHEMICAL CELL HAVING ELECTROLYTE WITH POLYMER LOCALIZED ON ELECTRODE SURFACE FACTORIAL INC. (US) 2023-09-07 WO disclosed
CN-103282438-A Polyamide 12 composition containing carbon nanotubes EVONIK DEGUSSA GMBH 2013-09-04 CN disclosed
US-20110257433-A1 LIQUIDS THE UNIVERSITY OF YORK (GB) 2011-10-20 US disclosed
EP-2322497-A1 Ionic liquids comprising nitrogen containing cations Innovia Films Limited (GB) 2011-05-18 EP disclosed
EP-1805131-B1 IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS INNOVIA FILMS LTD (GB) 2011-02-16 EP disclosed
US-20080221361-A1 Ionic Liquids BIONIQS LIMITED (GB) 2008-09-11 US disclosed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US disclosed