Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Dimethylaminoethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylaminoethanol SCHEMBL1131385 | 1.00 | MAPT (0.71) | MAPTALDH1A1CA5ACA5BPAOX | |
| Dimethylaminoethanol SCHEMBL1131908 | 0.92 | MAPT (0.67) | MAPTALDH1A1CA5ACA5BPAOX | |
| Dimethylaminoethanol SCHEMBL7791043 | 0.85 | MAPT (0.57) | MAPTALDH1A1PAOXCHRM2CHRM4 | |
| Sulfuric Acid SCHEMBL28411524 | 0.84 | CA5A (0.47) | MAPTALDH1A1CA5ACA5BPAOX | |
| Dimethylaminoethanol SCHEMBL16756236 | 0.84 | — | — | |
| Dimethylaminoethanol SCHEMBL2149038 | 0.84 | MAPT (1.00) | MAPTALDH1A1CA5ACA5BPAOX | |
| Dimethylaminoethanol SCHEMBL13169672 | 0.84 | — | — | |
| Dimethylaminoethanol SCHEMBL5945 | 0.84 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL1131469 | 0.83 | MAPT (0.55) | MAPTALDH1A1 | |
| Sulfuric Acid SCHEMBL17673109 | 0.82 | MAPT (0.45) | MAPTALDH1A1CA5ACA5BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3203839-A1 | ALKANOLAMINE SULFATE WATER CONDITIONERS | Huntsman Petrochemical LLC (US) | 2017-08-16 | — | — | EP | claimed |
| US-20170202215-A1 | Alkanolamine Sulfate Water Conditioners | HUNTSMAN PETROCHEMICAL LLC (US) | 2017-07-20 | — | — | US | claimed |
| WO-2016057170-A1 | ALKANOLAMINE SULFATE WATER CONDITIONERS | HUNTSMAN PETROCHEMICAL LLC (US) | 2016-04-14 | — | — | WO | claimed |
| US-8784686-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2014-07-22 | — | — | US | claimed |
| EP-1805131-B1 | IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS | INNOVIA FILMS LTD (GB) | 2011-02-16 | — | — | EP | claimed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | claimed |
| EP-4218730-B1 | LIPOSOMES USEFUL FOR DRUG DELIVERY | IPSEN BIOPHARM LTD (GB) | 2023-11-01 | — | — | EP | disclosed |
| EP-4218730-A1 | LIPOSOMES USEFUL FOR DRUG DELIVERY | Ipsen Biopharm Ltd. (GB) | 2023-08-02 | — | — | EP | disclosed |
| US-20230181567-A1 | Liposomes Useful for Drug Delivery | IPSEN BIOPHARM LTD. (GB) | 2023-06-15 | — | — | US | disclosed |
| CN-114901236-A | Flexible porous dissolvable solid sheet article with macropores and method of making same | 宝洁公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114867834-A | Flexible porous dissolvable solid sheet article with directly added microcapsules and method of making same | 宝洁公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114867447-A | Multilayer dissolvable solid article comprising solid particles for making multilayer dissolvable solid article | 宝洁公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114555483-A | Biodegradable and/or household compostable pouch containing solid article | 宝洁公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-1805131-B1 | IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS | INNOVIA FILMS LTD (GB) | 2011-02-16 | — | — | EP | disclosed |
| US-20080221361-A1 | Ionic Liquids | BIONIQS LIMITED (GB) | 2008-09-11 | — | — | US | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |
| US-20070116753-A1 | Liposomes useful for drug delivery | HERMES BIOSCIENCES, INC. (US) | 2007-05-24 | — | — | US | disclosed |
| US-20070110798-A1 | Liposomes useful for drug delivery to the brain | HERMES BIOSCIENCES, INC. (US) | 2007-05-17 | — | — | US | disclosed |
| EP-1746976-A1 | LIPOSOMES USEFUL FOR DRUG DELIVERY | Hermes Biosciences, Inc. (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005107712-A1 | LIPOSOMES USEFUL FOR DRUG DELIVERY | HERMES BIOSCIENCES, INC. (US) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181567-A1 | Liposomes Useful for Drug Delivery | ABHD16A, LIPA, AGPAT5 | CHRM2 4061/4885CHRM1 4500/4885CHRM3 3958/4885 |
| US-20170202215-A1 | Alkanolamine Sulfate Water Conditioners | SRM, SGMS1, SGMS2 | CHRM2 91/4885CHRM1 106/4885CHRM3 92/4885 |
| US-20070116753-A1 | Liposomes useful for drug delivery | ABHD16A, LIPA, AGPAT5 | CHRM2 4061/4885CHRM1 4500/4885CHRM3 3958/4885 |
| US-20070110798-A1 | Liposomes useful for drug delivery to the brain | ATP6V1B2, LPCAT3, AGPAT5 | CHRM2 3461/4885CHRM1 4255/4885CHRM3 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.