Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 10/20 | 0.40 |
| ▸ | NPY1R | P25929 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791103 | 0.81 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7788173 | 0.78 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL7791101 | 0.78 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7788172 | 0.78 | CRHR1 (0.46) | CRHR1NPY1R | |
| SCHEMBL7791822 | 0.74 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL7792985 | 0.72 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7788924 | 0.70 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL7557048 | 0.70 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL7792982 | 0.70 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL7681407 | 0.69 | CRHR1 (0.54) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031758-A1 | Substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives: selective neuropeptide Y receptor ligands | NEUROGEN CORPORATION | 2001-10-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031758-A1 | Substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives: selective neuropeptide Y receptor ligands | NPY1R, NPY2R, NPY5R | CRHR1 33/4885ACP1 968/4885NPY1R 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.