Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 16/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792985 | 0.79 | CRHR1 (0.48) | CRHR1SLC6A4 | |
| SCHEMBL7554809 | 0.74 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL7682689 | 0.74 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL7557048 | 0.73 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL7681407 | 0.72 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL1637888 | 0.72 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL7560969 | 0.71 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL7788887 | 0.71 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL7791103 | 0.70 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7555469 | 0.70 | CRHR1 (0.58) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031758-A1 | Substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives: selective neuropeptide Y receptor ligands | NEUROGEN CORPORATION | 2001-10-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031758-A1 | Substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives: selective neuropeptide Y receptor ligands | NPY1R, NPY2R, NPY5R | CRHR1 33/4885SLC6A4 381/4885HTR4 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.