Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27633472 | 0.84 | MAPT (0.48) | MAPTHTTBACE1BRD4PADI4 | |
| SCHEMBL1330600 | 0.84 | MAPT (0.48) | MAPTBACE1PADI4NOTUMBCAT2 | |
| SCHEMBL17604415 | 0.81 | BCAT2 (0.50) | MAPTMAP2BRD4BCAT2PARP1 | |
| SCHEMBL16007019 | 0.80 | HTT (0.54) | MAPTSMN1; SMN2HTTPADI4MEN1 | |
| SCHEMBL19952897 | 0.77 | MAPT (0.54) | MAPTSMN1; SMN2HSP90AA1HSP90AB1HTT | |
| SCHEMBL6503664 | 0.76 | ALDH1A1 (0.52) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL9223952 | 0.74 | HNF4A (0.44) | MAPTNOTUMBCAT2ALDH1A1 | |
| SCHEMBL29750764 | 0.74 | CCNC (0.51) | MAPTSMN1; SMN2HSP90AA1HSP90AB1HTT | |
| SCHEMBL16056793 | 0.74 | STAT3 (0.44) | MAPTHTTPADI4MEN1KMT2A | |
| SCHEMBL28820009 | 0.72 | HTT (0.40) | MAPTSMN1; SMN2HTTPADI4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110841033-A | Traditional Chinese medicine health-care waistband for preventing and treating blood deficiency and cold coagulation type dysmenorrhea and preparation method thereof | 河北中医学院 | 2020-02-28 | — | — | CN | disclosed |
| CN-109020814-A | A kind of polysubstituted 10- hydroxyl is luxuriant and rich with fragrance and its derivative and its synthetic method | 南开大学 | 2018-12-18 | — | — | CN | disclosed |
| US-20010021714-A1 | THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | ENCYSIVE PHARMACEUTICALS INC. | 2001-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021714-A1 | THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | EDNRA, EDNRB, NPSR1 | MAPT 4280/4885SMN1; SMN2 3907/4885HSP90AA1 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.