SCHEMBL7791503

SCHEMBL7791503

C=Cc1ccccc1CC(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792768 0.95 ALDH1A1 (0.34) ALDH1A1
SCHEMBL7790762 0.83 LMNA (0.35) ALDH1A1
SCHEMBL7792761 0.81 ALDH1A1 (0.40) ALDH1A1
SCHEMBL7783036 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL8625966 0.79 LMNA (0.32) ALDH1A1
SCHEMBL25513626 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL25513622 0.77 ALDH1A1 (0.32) ALDH1A1
SCHEMBL25513619 0.77 ALDH1A1 (0.32) ALDH1A1
SCHEMBL7787987 0.75 ALDH1A1 (0.35) ALDH1A1
SCHEMBL9602136 0.73 RIPK1 (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890636-B1 Culture vessel MENICON CO LTD (JP) 2001-10-31 EP disclosed
US-6018001-A ACID TREATMENT OF A CONTACT LENS WHICH IS A COPOLYMER OF ASUGAR KETAL-CONTAINING (METH)ACRYLATE AND A SUGAR GLYCEROL KETAL-CONTAINING (METH)ACRYLATE AND A CO-MONOMER CONTAINING SILICON AND FLUORINE-MONOMER; OXYGEN PERMEABILITY MENICON CO., LTD. (JP) 2000-01-25 US disclosed
EP-0892297-A1 PROCESS FOR PRODUCING CONTACT LENS WITH HYDROPHILIC SURFACE AND CONTACT LENS OBTAINED THEREBY MENICON CO., LTD. (JP) 1999-01-20 EP disclosed
EP-0890636-A1 Culture vessel Menicon Co., Ltd. (JP) 1999-01-13 EP disclosed