Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.53 |
| ▸ | NOS1 | P29475 | 5/20 | 0.50 |
| ▸ | NOS2 | P35228 | 4/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ARG2 | P78540 | 4/20 | 0.48 |
| ▸ | ARG1 | P05089 | 3/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362969 | 1.00 | GSR (0.53) | GSRNOS1NOS2DDAH1ALDH1A1 | |
| SCHEMBL3486168 | 0.98 | GSR (0.55) | GSRNOS1NOS2DDAH1ALDH1A1 | |
| SCHEMBL28007955 | 0.87 | GRIK1 (0.59) | GSRNOS1NOS2DDAH1ALDH1A1 | |
| SCHEMBL27363028 | 0.87 | GRIK1 (0.59) | GSRNOS1NOS2DDAH1ALDH1A1 | |
| SCHEMBL28007603 | 0.87 | GRIK1 (0.59) | GSRNOS1NOS2DDAH1ALDH1A1 | |
| SCHEMBL28921485 | 0.87 | GRIK1 (0.59) | GSRNOS1NOS2DDAH1ALDH1A1 | |
| SCHEMBL28007614 | 0.87 | GRIK1 (0.59) | GSRNOS1NOS2DDAH1ALDH1A1 | |
| SCHEMBL28818201 | 0.87 | GRIK1 (0.59) | GSRNOS1NOS2DDAH1ALDH1A1 | |
| SCHEMBL9259268 | 0.85 | ALDH1A1 (0.46) | GSRNOS1NOS2DDAH1ALDH1A1 | |
| SCHEMBL15342759 | 0.84 | GRIK1 (0.60) | GSRNOS1DDAH1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200289611-A1 | Methods and Compositions for the Inhibition of Quorum Sensing in Bacterial Infections | UNIVERSITY OF NORTH CAROLINA AT GREENSBORO | 2020-09-17 | — | — | US | disclosed |
| WO-2019219938-A1 | FMOC PROTECTED (2S)-2-AMINO-8-[(1,1-DIMETHYLETHOXY)AMINO]-8-OXO-OCTANOIC ACID, (S)-2-AMINO-8-OXONONANOIC ACID AND (S)-2-AMINO-8-OXODECANOIC ACID FOR PEPTIDE SYNTHESIS | THE UNIVERSITY COURT OF THE UNIVERISTY OF GLASGOW (GB) | 2019-11-21 | — | — | WO | disclosed |
| WO-2017197303-A1 | METHODS AND COMPOSITIONS FOR THE INHIBITION OF QUORUM SENSING IN BACTERIAL INFECTIONS | UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2017-11-16 | — | — | WO | disclosed |
| EP-1150998-A1 | PROCESS FOR THE PREPARATION OF CYCLIC TETRAPEPTIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047608-A1 | PROCESS FOR THE PREPARATION OF CYCLIC TETRAPEPTIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200289611-A1 | Methods and Compositions for the Inhibition of Quorum Sensing in Bacterial Infections | PYCARD, LASP1, API5 | GSR 3004/4885NOS1 633/4885NOS2 480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.