Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657509 | 0.81 | KMT2A (0.54) | KDM4EHSD17B10ELANEPRTN3ALDH1A1 | |
| SCHEMBL2499921 | 0.80 | LMNA (0.67) | LMNAKDM4EHSD17B10GAAALDH1A1 | |
| SCHEMBL1688339 | 0.78 | METAP2 (0.71) | LMNAKDM4EHSD17B10ALDH1A1HPGD | |
| Lithium Ion SCHEMBL6112283 | 0.77 | LMNA (0.67) | LMNAKDM4EHSD17B10GAAALDH1A1 | |
| Zinc Ion SCHEMBL9443911 | 0.77 | LMNA (0.67) | LMNAKDM4EHSD17B10GAAALDH1A1 | |
| SCHEMBL15821566 | 0.77 | LMNA (0.67) | LMNAKDM4EHSD17B10GAAALDH1A1 | |
| SCHEMBL8567723 | 0.76 | HTR2C (0.62) | ALDH1A1FFAR4KMT2AMEN1 | |
| SCHEMBL1495939 | 0.76 | FFAR4 (0.80) | LMNAKDM4EHSD17B10GAAELANE | |
| SCHEMBL17429526 | 0.76 | LMNA (0.58) | LMNAKDM4EHSD17B10GAAALDH1A1 | |
| SCHEMBL5634989 | 0.75 | KDM4E (0.50) | KDM4EHSD17B10GAAELANEPRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849262-B1 | Aminophenyl ketone derivatives and a method for the preparation thereof | AMERICAN CYANAMID CO (US) | 2001-10-17 | — | — | EP | disclosed |
| US-6127576-A | Aminophenyl ketone derivatives and a method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0849262-A1 | Aminophenyl ketone derivatives and a method for the preparation thereof | American Cyanamid Company (US) | 1998-06-24 | — | — | EP | disclosed |