Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855770 | 0.92 | KCNA5 (0.65) | METAP2LMNAMCL1ALDH1A1KDM4E | |
| SCHEMBL1466906 | 0.89 | ALDH1A1 (0.72) | METAP2LMNAMCL1ALDH1A1KDM4E | |
| SCHEMBL27995 | 0.87 | ALDH1A1 (0.74) | METAP2LMNAALDH1A1HSD17B10KMT2A | |
| Zinc Ion SCHEMBL9443911 | 0.86 | LMNA (0.67) | METAP2LMNAALDH1A1KDM4EHSD17B10 | |
| Lithium Ion SCHEMBL6112283 | 0.86 | LMNA (0.67) | METAP2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15821566 | 0.86 | LMNA (0.67) | METAP2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9402809 | 0.86 | ACLY (0.73) | METAP2LMNAMCL1ALDH1A1KDM4E | |
| SCHEMBL2499921 | 0.86 | LMNA (0.67) | METAP2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL16127963 | 0.86 | ALDH1A1 (0.69) | METAP2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3561943 | 0.85 | LMNA (0.58) | METAP2LMNAMCL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058977-A1 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | INSTITUTE OF MATERIA MEDIC, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2004-03-25 | — | — | US | claimed |
| CN-1127482-C | Sulfuryl diphenyl indole compound and preparation process and use in medicine | INST OF MEDICINE CHINESE ACADE (CN) | 2003-11-12 | — | — | CN | claimed |
| CN-1333206-A | Sulfuryl diphenyl indole compound and preparation process and use in medicine | INST OF MEDICINE CHINESE ACADE (CN) | 2002-01-30 | — | — | CN | claimed |
| EP-0341536-B1 | MIXTURES OF ALKENYLSUCCINIC ACIDS, ARYLSULFONYLANTHRANILIC ACIDS AND ALKANOL AMINES AND THEIR USE AS CORROSION INHIBITORS IN AQUEOUS SYSTEMS | BASF Aktiengesellschaft (DE) | 1992-01-02 | — | — | EP | claimed |
| EP-0341536-A1 | Mixtures of alkenylsuccinic acids, arylsulfonylanthranilic acids and alkanol amines and their use as corrosion inhibitors in aqueous systems | BASF Aktiengesellschaft (DE) | 1989-11-15 | — | — | EP | claimed |
| US-12065421-B2 | Inhibitors of oplophorus luciferase-derived bioluminescent complexes | PROMEGA CORPORATION (US) | 2024-08-20 | — | — | US | disclosed |
| EP-4140991-B1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | PROMEGA CORP (US) | 2024-05-15 | — | — | EP | disclosed |
| EP-4140991-A1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | Promega Corporation (US) | 2023-03-01 | — | — | EP | disclosed |
| US-20220365086-A1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | PROMEGA CORPORATION | 2022-11-17 | — | — | US | disclosed |
| EP-3802514-B1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | PROMEGA CORP (US) | 2022-08-03 | — | — | EP | disclosed |
| US-11390599-B2 | Inhibitors of oplophorus luciferase-derived bioluminescent complexes | PROMEGA CORPORATION (US) | 2022-07-19 | — | — | US | disclosed |
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |
| WO-2000078145-A1 | MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-28 | — | — | WO | disclosed |
| US-6140513-A | Color forming dye precursor, composition containing the same and color forming heat-sensitive recording material | MITSUBISHI PAPER MILLS LIMITED (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0308820-B1 | ZINC, LEAD, AND/OR CALCIUMSALTS OF CARBOXYLIC ACIDS AND THEIR USE AS ANTICORROSIVE AGENTS | BASF Lacke + Farben AG (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4999134-A | For alkyd resin coating systems, aqueous and nonaqueous | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0308820-A1 | Zinc, lead, and/or calciumsalts of carboxylic acids and their use as anticorrosive agents | BASF Lacke + Farben AG (DE) | 1989-03-29 | — | — | EP | disclosed |
| EP-0212010-A1 | Color developers for pressure-sensitive or heat-sensitive recording papers | THE STANDARD REGISTER COMPANY (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4623391-A | COMPOUNDS HAVING ELECTRON-WITH DRAWING GROUPS WITHIN FIVE ATOMS OF A SULFANAMIDE | THE STANDARD REGISTER COMPANY (US) | 1986-11-18 | — | — | US | disclosed |
| US-4531139-A | Color developers for pressure-sensitive or heat-sensitive recording papers | THE STANDARD REGISTER COMPANY (US) | 1985-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220365086-A1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | LUC7L2, LYPLAL1, GUSB | METAP2 820/4885LMNA 1478/4885MCL1 1048/4885 |
| US-12065421-B2 | Inhibitors of oplophorus luciferase-derived bioluminescent complexes | LUC7L2, LYPLAL1, GUSB | METAP2 820/4885LMNA 1478/4885MCL1 1048/4885 |
| US-20040058977-A1 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | PTGS2, PTGES2, PTGER2 | METAP2 1188/4885LMNA 3726/4885MCL1 2311/4885 |
| US-11390599-B2 | Inhibitors of oplophorus luciferase-derived bioluminescent complexes | LUC7L2, LYPLAL1, GUSB | METAP2 820/4885LMNA 1478/4885MCL1 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.